Title:
生物学的製造の多変量スペクトル分析および監視
Document Type and Number:
Japanese Patent JP7326307
Kind Code:
B2
Abstract:
The disclosure features methods that include obtaining a vibrational spectrum of a solution in a biological manufacturing system, analyzing the vibrational spectrum using a first chemometrics model to determine a value of a first quality attribute associated with the solution, analyzing the vibrational spectrum using a second chemometrics model to determine a value of a second quality attribute associated with the solution, and adjusting at least one parameter of a purification unit of the biological manufacturing system based on at least one of the values of the first and second quality attributes.
Inventors:
Danuka Plasti Wasara Santuri
Jug Dish Sea Tewari
Shueshen Kang
Marina Hincapie
Shaun El Barrett
Julie Susanne Pollock
Jug Dish Sea Tewari
Shueshen Kang
Marina Hincapie
Shaun El Barrett
Julie Susanne Pollock
Application Number:
JP2020545704A
Publication Date:
August 15, 2023
Filing Date:
March 01, 2019
Export Citation:
Assignee:
GENZYME CORPORATION
International Classes:
G01N21/552; C07K1/16; C12M1/00; C12M1/36; G01N30/46
Domestic Patent References:
| JP2008526203A | ||||
| JP2008504845A | ||||
| JP2012520078A | ||||
| JP2013505462A | ||||
| JP4638153B2 |
Foreign References:
| CN104406836A | ||||
| EP3173782A1 | ||||
| WO2017174580A1 |
Attorney, Agent or Firm:
Junji Yuda
Noriyuki Takebayashi
Noriyuki Takebayashi