Title:
活性化誘導シチジンデアミナーゼ（ＡＩＤ）の変異体及び使用方法
Document Type and Number:
Japanese Patent JP5683566
Kind Code:
B2
Abstract:
The invention provides functional mutants of activation-induced cytidine deaminase (AID) protein that have increased activity as compared to a wild-type AID protein. The invention also provides nucleic acids encoding the functional AID mutants, and vectors and cells comprising the nucleic acids. The invention further provides methods of using the functional mutant AID proteins.
Inventors:
ワン、メン
ヤン、ジチェン
ラダ、クリスティーナ
ニューバーガー、マイケル
ヤン、ジチェン
ラダ、クリスティーナ
ニューバーガー、マイケル
Application Number:
JP2012502830A
Publication Date:
March 11, 2015
Filing Date:
April 05, 2010
Export Citation:
Assignee:
メディカル リサーチ カウンシル
International Classes:
C12N15/09; A01K67/027; C12N1/15; C12N1/19; C12N1/21; C12N5/10; C12N9/78
Attorney, Agent or Firm:
Takashima 1
Kyoko Doi
Kamata 光宜
Tamura Yasaka child
Kenji Yamamoto
Murata Miyuki
Koike 順造
Hirofumi Toma
Kyoko Doi
Kamata 光宜
Tamura Yasaka child
Kenji Yamamoto
Murata Miyuki
Koike 順造
Hirofumi Toma