Mutation and rearrangement of a mitochondria as a diagnostic tool for detection of sun exposure, a prostatic cancer, and other cancers

Title:

Mutation and rearrangement of a mitochondria as a diagnostic tool for detection of sun exposure, a prostatic cancer, and other cancers

Document Type and Number:

Japanese Patent JP6134890

Kind Code:

B2

Abstract:

Mitochondrial DNA (mtDNA) deletions useful for the detection of cancers and sun exposure are provided. In particular, methods and kits for detecting mitochondrial DNA deletions for the early detection, diagnosis and progression of prostate cancer, sun exposure and non-melonoma skin cancer are provided.

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Inventors:

Par, ryan
Seyer, robert
Gabriel, Dakubo
Maki jennifer
Robinson, Kelly
Magra, andrea
Brig
Harbottle, Andrew
Birch-Mashan, Mark

Application Number:

JP2012101409A

Publication Date:

May 31, 2017

Filing Date:

April 26, 2012

Export Citation:

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Assignee:

MDNA Life Sciences Inc.

International Classes:

C12N15/09; C12M1/00; C12Q1/68; G01N33/574; G01N37/00

Foreign References:

WO2002101086A2

Other References:

J.Invest.Dermatol.,Vol.123(2004)p.1020-4
J.Invest.Dermatol.,Vol.122(2004)p.1518-21
Br.J.Cancer,Vol.88(2003)p.90-5

Attorney, Agent or Firm:

Yusuke Hiraki
Satoshi Fujita
Eiichi Arai
Natsuo Tanaka
Naoko Kikuta

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