Title:
PDGF受容体阻害剤としてのN-置換三環状3-アミノピラゾール
Document Type and Number:
Japanese Patent JP2006502097
Kind Code:
A
Abstract:
The invention is directed to N-substituted tricyclic 3-AMINOPYRAZOLE derivatives, which are useful as inhibitors of platelet-derived growth factor receptor (PDGF-R) kinase, and methods for the preparation of said derivatives. The present invention is further directed to pharmaceutical compositions comprising the compounds of the present invention and to methods for treating conditions such as tumors and other cell proliferative disorders.
Inventors:
Ho Young, Chi Young
Bran Mark, Bent Anders
Emanuel, Stiletto
Garemo Giunia, Robert A.
Diana El, Ji Young-son
Ludovic, Donald Davryu
Maha roof, Umar
May, JAM
Jessie L
Strobel, Eric Day
Tauman, Robert Davryu
Yen Co
Bran Mark, Bent Anders
Emanuel, Stiletto
Garemo Giunia, Robert A.
Diana El, Ji Young-son
Ludovic, Donald Davryu
Maha roof, Umar
May, JAM
Jessie L
Strobel, Eric Day
Tauman, Robert Davryu
Yen Co
Application Number:
JP2004505342A
Publication Date:
January 19, 2006
Filing Date:
May 13, 2003
Export Citation:
Assignee:
JANSSEN PHARMACEUTICA NAAMLOZE VENNOOTSCHAP
International Classes:
C07D231/54; A61F2/82; A61K31/416; A61K31/4162; A61K31/424; A61K31/4439; A61K31/454; A61K31/496; A61K31/506; A61K31/5377; A61K31/7056; A61L31/00; A61P9/00; A61P9/10; A61P11/00; A61P13/12; A61P19/02; A61P27/02; A61P29/00; A61P35/00; A61P35/02; A61P35/04; A61P43/00; C07D231/56; C07D233/54; C07D401/12; C07D401/14; C07D403/04; C07D403/12; C07D405/04; C07D405/12; C07D413/12; C07D491/04; C07D491/048; C07D491/052; C07D491/056; C07D495/04; C07D498/04; C07F9/6503; C07H17/02; C07H19/04; C12Q1/48; G01N33/15; G01N33/50
Attorney, Agent or Firm:
Heikichi Odashima