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Title:
N-ARYL DIAZASPIROCYCLIC COMPOUND AND METHOD OF PREPARATION AND USE THEREOF
Document Type and Number:
Japanese Patent JP2011088896
Kind Code:
A
Abstract:

To provide pharmaceutical compositions, each including a compound which influences nicotinic cholinergic receptor, especially which is useful for treating the states and disorders relating to functional disturbance of the central nervous system and automatic nervous system.

One of the pharmaceutical compositions includes a compound represented by the following formula (wherein the ring is selected so as to be diazaspirononane; R is hydrogen, lower alkyl, acyl, alkoxy carbonyl or aryloxy carbonyl; and Cy is pyridine, etc.) or its medically allowable salt. Another pharmaceutical composition includes a compound selected from the group consisting of 7-(3-pyridyl)-1,7-diazaspiro [4.4] nonane, 6-(3-pyridyl)-1,6-diazaspiro [3.5] nonane, etc. or its medically allowable salt.


Inventors:
BHATTI BALWINDER S
MILLER CRAIG H
SCHMITT JEFFREY D
Application Number:
JP2010248200A
Publication Date:
May 06, 2011
Filing Date:
November 05, 2010
Export Citation:
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Assignee:
TARGACEPT INC
International Classes:
A61K31/4439; A61K31/444; A61K31/506; A61P1/02; A61P1/04; A61P1/16; A61P7/00; A61P9/10; A61P11/00; A61P11/06; A61P19/02; A61P25/00; A61P25/02; A61P25/08; A61P25/14; A61P25/16; A61P25/18; A61P25/22; A61P25/24; A61P25/28; A61P29/00; A61P31/04; A61P31/10; A61P31/12; A61P31/18; A61P35/00; A61P37/06; A61P43/00; C07D453/00; C07D471/10; C07D487/10; C07D487/20
Attorney, Agent or Firm:
Kawaguchi International Patent Office