Title:
ブラジキニン拮抗薬として有用なメチル上に置換基を有するN-ビフェニルメチルアミノシクロアルカンカルボキサミド誘導体
Document Type and Number:
Japanese Patent JP2005517006
Kind Code:
A
Abstract:
N-Biphenyl(substituted methyl)aminocycloalkanecarboxamide derivatives are bradykinin B1 antagonists or inverse agonists useful in the treatment or prevention of symptoms such as pain and inflammation associated with the bradykinin B1 pathway.
Inventors:
Utd, Michael Earl
Anthony, Neville Jei
Bock, Mark Gee
Fuen, Don-May
Kudatsuk, Scott Day
Sue, Dai Shii
Way, Jeannie Miu-Chiyun
Anthony, Neville Jei
Bock, Mark Gee
Fuen, Don-May
Kudatsuk, Scott Day
Sue, Dai Shii
Way, Jeannie Miu-Chiyun
Application Number:
JP2003565952A
Publication Date:
June 09, 2005
Filing Date:
February 04, 2003
Export Citation:
Assignee:
MERCK & COMPANY INCOPORATED
International Classes:
A61K31/166; A61K31/24; A61K31/41; A61K31/42; A61K31/4245; A61K31/505; A61P1/02; A61P1/04; A61P1/16; A61P1/18; A61P9/10; A61P11/00; A61P11/06; A61P11/08; A61P13/10; A61P13/12; A61P17/02; A61P17/06; A61P19/02; A61P19/08; A61P21/00; A61P25/04; A61P25/06; A61P25/28; A61P27/16; A61P29/00; A61P31/04; A61P35/00; A61P37/08; C07C237/24; C07D213/82; C07D239/28; C07D257/04; C07D261/18; C07D271/06; C07D403/12; C07D413/12; (IPC1-7): C07C237/24; A61K31/166; A61K31/24; A61K31/41; A61K31/42; A61K31/4245; A61K31/505; A61P1/02; A61P1/04; A61P1/16; A61P1/18; A61P9/10; A61P11/00; A61P11/06; A61P11/08; A61P13/10; A61P13/12; A61P17/02; A61P17/06; A61P19/02; A61P19/08; A61P21/00; A61P25/04; A61P25/06; A61P25/28; A61P27/16; A61P29/00; A61P31/04; A61P35/00; A61P37/08; C07D239/28; C07D257/04; C07D261/18; C07D271/06; C07D403/12; C07D413/12
Attorney, Agent or Firm:
Yoshio Kawaguchi
Akio Ichiiri
Makoto Ono
Katsuma Osaki
Mitsuaki Tsubokura
Akio Ichiiri
Makoto Ono
Katsuma Osaki
Mitsuaki Tsubokura