Title:
インテグリンのそれの受容体への結合を阻害するN,N-ジ置換アミド
Document Type and Number:
Japanese Patent JP4949552
Kind Code:
B2
Abstract:
A method for the inhibition of the binding of alpha 4 beta 1 integrin to its receptors, for example VCAM-1 (vascular cell adhesion molecule-1) and fibronectin; compounds that inhibit this binding; pharmaceutically active compositions comprising such compounds; and the use of such compounds either as above, or in formulations for the control or prevention of diseases states in which alpha 4 beta 1 is involved.
Inventors:
Katsar, Jiamal M
B. Dateger, Ronald J. Aye
Grabbe, Baneza Oh
Rin, Yuchun
Robert Buoy, Market
Rajyu, Boa Gee
Ian El, Scott
Corgan, Timothy Pee
B. Dateger, Ronald J. Aye
Grabbe, Baneza Oh
Rin, Yuchun
Robert Buoy, Market
Rajyu, Boa Gee
Ian El, Scott
Corgan, Timothy Pee
Application Number:
JP2000543456A
Publication Date:
June 13, 2012
Filing Date:
April 15, 1999
Export Citation:
Assignee:
Encouraging Pharmaceuticals, Incorporated
International Classes:
C07D233/02; A61K31/16; C07D317/44; A61K31/357; A61K31/36; A61K31/38; A61K31/381; A61K31/404; A61K31/4184; A61K31/425; A61K31/427; A61K31/443; A61K31/4433; A61K31/4525; A61K31/495; A61K31/496; A61K31/5377; A61P1/04; A61P3/10; A61P9/10; A61P11/06; A61P17/00; A61P19/02; A61P25/00; A61P29/00; A61P35/00; A61P35/02; A61P37/06; A61P37/08; A61P43/00; C07C233/00; C07D277/30; C07D317/60; C07D333/20; C07D333/24; C07D333/36; C07D405/00; C07D405/12; C07D405/14; C07D409/00; C07D409/12; C07D409/14; C07D413/14; C07D417/14
Domestic Patent References:
| JP6321985A | ||||
| JP6298797A | ||||
| JP6510985A | ||||
| JP6192273A |
Attorney, Agent or Firm:
Toru Ishikawa