Title:
N-(インドールエチル)シクロアミン化合物
Document Type and Number:
Japanese Patent JP2006511522
Kind Code:
A
Abstract:
N-(indolethyl-)cycloamine compounds of the formula (I): in which R1', R1'' X, Ar, and n have a meaning indicated in Claim 1, are serotonin reuptake inhibitors (SSRIs) and effectors of the serotonergic receptors 5-HT1A and 5-HT2A. They are therefore suitable for the prophylaxis or treatment of various diseases of the central nervous system, such as depression, dyskinesia, Parkinson's disease, dementia, strokes, schizophrenia, Alzheimer's disease, Lewy bodies dementia, Huntington's disease, Tourette's syndrome, anxiety, learning and memory impairment, pain, sleeping disorders and neurodegenerative diseases.
Inventors:
Heinrich, Timo
Bettchel, Henink
Seaman, Kai
Herzemann, Gunter
Fun Amsterdam, Christoph
Bartsk, Geld
Live Rock, Joachim
Seyfried, christophe
Bettchel, Henink
Seaman, Kai
Herzemann, Gunter
Fun Amsterdam, Christoph
Bartsk, Geld
Live Rock, Joachim
Seyfried, christophe
Application Number:
JP2004559727A
Publication Date:
April 06, 2006
Filing Date:
November 27, 2003
Export Citation:
Assignee:
Merck Patent Gesellschaft mit beschraenkter Haftung
International Classes:
C07D209/14; A61K31/496; A61P9/10; A61P25/00; A61P25/04; A61P25/14; A61P25/16; A61P25/18; A61P25/20; A61P25/22; A61P25/24; A61P25/28; A61P43/00; C07D209/10; C07D209/18; C07D209/42; C07D405/12; C07D417/12
Attorney, Agent or Firm:
Kiyoji Kuzuwa