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Title:
N-置換ベンゼンスルホンアミド
Document Type and Number:
Japanese Patent JP2007528405
Kind Code:
A
Abstract:
The invention provides N-substituted benzenesulfonamides for use in treating or preventing cognitive disorders, such as Alzheimer's Disease. Compounds of particular interest are defined by Formula (I), wherein R1, R2, R3, R4, and R3, are as described in the specification. The invention also encompasses pharmaceutical compositions comprising compounds of Formula (I) as well as methods of treating cognitive disorders, including Alzheimer's disease using compounds of Formula (I).

Inventors:
Martin, Martin
Margg, Jennifer
Application Number:
JP2007502969A
Publication Date:
October 11, 2007
Filing Date:
March 11, 2005
Export Citation:
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Assignee:
PHARMACIA & UPJOHN COMPANY
International Classes:
C07C311/16; A61K31/18; A61K31/185; A61K31/341; A61K31/343; A61K31/352; A61K31/357; A61K31/36; A61K31/40; A61K31/4045; A61K31/415; A61K31/4164; A61K31/4172; A61K31/426; A61K31/44; A61K31/445; A61K31/4468; A61P25/16; A61P25/28; C07C311/15; C07C311/17; C07C311/18; C07C311/19; C07C311/20; C07C311/21; C07C311/31; C07C311/51; C07C317/32; C07D207/09; C07D209/14; C07D211/58; C07D213/52; C07D231/06; C07D231/42; C07D233/16; C07D277/20; C07D277/24; C07D277/36; C07D307/52; C07D307/81; C07D311/58; C07D317/58; C07D319/10
Domestic Patent References:
JP2001502330A2001-02-20
JP2001233847A2001-08-28
JPH10147564A1998-06-02
JP2002537376A2002-11-05
JP2002537376A2002-11-05
Foreign References:
WO2003053912A12003-07-03
WO2002089749A22002-11-14
WO2003103660A12003-12-18
WO2003053912A12003-07-03
WO2002089749A22002-11-14
Other References:
JPN6010072201; Journal of the American Chemical Society 124(46), 2002, p.13856-13863
JPN6010072204; Journal of Organic Chemistry 43(7), 1978, p.1337-1342
JPN6010072201; Journal of the American Chemical Society 124(46), 2002, p.13856-13863
JPN6010072204; Journal of Organic Chemistry 43(7), 1978, p.1337-1342
Attorney, Agent or Firm:
Hideto Asamura
Hajime Asamura
Naganuma Akio
Yukihiro Ikeda