N-置換非アリール複素環アミジル系NMDA/NR2B拮抗薬

Japanese Patent JP2005511478

A

Compounds represented by Formula (I): or pharmaceutically acceptable salts thereof, are effective as NMDA NR2B antagonists useful for relieving pain.

Rivaton, Niger El Jei
Butcher, Jiyoung Daburi
Matsukin Tire, Challes Jei
Claybone, Christopher F
Claremon, David A
Matsucoree, Jiyoung Ai
Romano, Giorojif Jei
Thompson, Wayne
Manson, Peter M

JP2002578967A

April 28, 2005

April 02, 2002

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MERCK & COMPANY INCOPORATED

A61K31/40; A61K31/445; A61K31/451; A61K31/4535; A61K31/454; A61K31/4545; A61K31/4709; A61K31/4725; A61K31/495; A61K31/496; A61K31/497; A61K31/501; A61K31/506; A61K31/519; A61K31/52; A61K31/5375; A61K31/5377; A61K31/55; A61K31/553; A61P9/10; A61P25/04; A61P25/06; A61P25/16; A61P25/18; A61P25/22; A61P25/24; A61P27/06; A61P27/16; C07D207/09; C07D211/26; C07D211/38; C07D211/42; C07D211/96; C07D241/04; C07D265/30; C07D267/10; C07D401/12; C07D401/14; C07D405/14; C07D409/12; C07D409/14; C07D413/12; C07D417/04; C07D417/12; C07D417/14; C07D471/04; C07D473/00; C07D487/04; (IPC1-7): C07D207/09; A61K31/40; A61K31/445; A61K31/451; A61K31/4535; A61K31/454; A61K31/4545; A61K31/4709; A61K31/4725; A61K31/495; A61K31/496; A61K31/497; A61K31/501; A61K31/506; A61K31/519; A61K31/52; A61K31/5375; A61K31/5377; A61K31/55; A61K31/553; A61P9/10; A61P25/04; A61P25/06; A61P25/16; A61P25/18; A61P25/22; A61P25/24; A61P27/06; A61P27/16; C07D211/26; C07D211/38; C07D211/42; C07D211/96; C07D241/04; C07D265/30; C07D267/10; C07D401/12; C07D401/14; C07D405/14; C07D409/12; C07D409/14; C07D413/12; C07D417/04; C07D417/12; C07D417/14; C07D471/04; C07D473/00

Yoshio Kawaguchi
Akio Ichiiri
Makoto Ono
Katsuma Osaki
Mitsuaki Tsubokura

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