Title:
MEK阻害剤としてのN3アルキル化ベンズイミダゾール誘導体
Document Type and Number:
Japanese Patent JP2005530709
Kind Code:
A
Abstract:
Pharmaceutical compositions comprising a compound of the formula I
selected from 6-(4-bromo-2-fluoro-phenylamino)-7-fluoro-3-methyl-3H-benzoimidazole-5-carboxylic acid (2-hydroxy-ethoxy)-amide and pharmaceutically acceptable salts thereof,
for use in the treatment of hyperproliferative diseases, such as cancer and inflammation, in mammals.
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Inventors:
Wallace, Eli, M.
Rishikatos, Joseph, Pee.
Harley, Bryan, Tee.
Marlowe, Allison, Elle.
Rishikatos, Joseph, Pee.
Harley, Bryan, Tee.
Marlowe, Allison, Elle.
Application Number:
JP2003575967A
Publication Date:
October 13, 2005
Filing Date:
March 13, 2003
Export Citation:
Assignee:
VentiRx Pharmaceuticals,Inc.
International Classes:
C07D235/08; A61K31/4184; A61K31/422; A61K31/4245; A61K31/427; A61K31/4439; A61K31/454; A61K31/496; A61K31/5377; A61K31/541; A61P1/00; A61P1/18; A61P3/10; A61P9/08; A61P9/10; A61P13/08; A61P13/12; A61P17/00; A61P17/04; A61P17/06; A61P19/02; A61P27/02; A61P29/00; A61P35/00; A61P43/00; C07D235/04; C07D235/06; C07D401/06; C07D401/12; C07D401/14; C07D403/04; C07D403/06; C07D403/12; C07D405/06; C07D413/04; C07D413/06; C07D417/06; C07D417/12; (IPC1-7): C07D235/08; A61K31/4184; A61K31/422; A61K31/4245; A61K31/427; A61K31/4439; A61K31/454; A61K31/496; A61K31/5377; A61K31/541; A61P1/00; A61P1/18; A61P3/10; A61P9/08; A61P9/10; A61P13/08; A61P13/12; A61P17/00; A61P17/04; A61P17/06; A61P19/02; A61P27/02; A61P29/00; A61P35/00; A61P43/00; C07D401/06; C07D401/12; C07D403/04; C07D405/06; C07D413/04; C07D413/06; C07D417/06; C07D417/12
Attorney, Agent or Firm:
Hideto Asamura
Hajime Asamura
Naganuma Akio
Yukihiro Ikeda
Hajime Asamura
Naganuma Akio
Yukihiro Ikeda