Title:
ラミノパシー、老化及び癌を治療又は予防するためのＮＡＴ１０モジュレーター
Document Type and Number:
Japanese Patent JP2017511333
Kind Code:
A
Abstract:
本発明は、ラミンA及び／もしくはラミンC欠乏又はLMNA変異に関連した障害、例えばラミノパシー、早期老化障害、正常老化及び癌(低レベルのLMNA発現により特徴付けられる癌など)などの治療又は予防における化合物に関する。【選択図】図１
Inventors:
Delphine Lawrence Danielle Larieu
Rafael Joel Rodriguez
Sebastian Frederik Stefane Briton
Stephen Philip Jackson
Rafael Joel Rodriguez
Sebastian Frederik Stefane Briton
Stephen Philip Jackson
Application Number:
JP2016560492A
Publication Date:
April 20, 2017
Filing Date:
April 02, 2015
Export Citation:
Assignee:
Cambridge Enterprise Limited
Center National de la Lechatier Charter
Center National de la Lechatier Charter
International Classes:
C07D277/50; A61K31/426; A61K31/549; A61K45/00; A61P1/16; A61P3/10; A61P9/00; A61P17/00; A61P21/04; A61P35/00; A61P43/00; C07D285/16
Domestic Patent References:
| JP2008538107A | 2008-10-09 | |||
| JPH07133264A | 1995-05-23 | |||
| JPS61140583A | 1986-06-27 |
Other References:
SECCI, D. ET AL., BIOORG. MED. CHEM., vol. 22, JPN6018040133, 26 January 2014 (2014-01-26), pages 1680 - 1689, ISSN: 0004102886
TRISCIUOGLIO, D. ET AL., CLIN. CANCER RES., vol. 18, no. 2, JPN6018040135, 2012, pages 475 - 486, ISSN: 0004102887
CHIMENTI, F. ET AL., BIOORG. MED. CHEM., vol. 18, JPN6018040137, 2010, pages 5063 - 5070, ISSN: 0004102888
TRISCIUOGLIO, D. ET AL., CLIN. CANCER RES., vol. 18, no. 2, JPN6018040135, 2012, pages 475 - 486, ISSN: 0004102887
CHIMENTI, F. ET AL., BIOORG. MED. CHEM., vol. 18, JPN6018040137, 2010, pages 5063 - 5070, ISSN: 0004102888
Attorney, Agent or Firm:
Toru Ishikawa