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Title:
ND2 peptide and a therapeutic method of diseases of the nervous system
Document Type and Number:
Japanese Patent JP6073230
Kind Code:
B2
Abstract:
The invention is based in part on identifying a core region of ND2 responsible for interacting with Src to within residues 289-321 of ND2 and more particularly residues 307-321 or 310-321 of ND2. Peptides including, overlapping or from within this region can be used to inhibit ND2 interaction with Src Inhibition of this interaction is useful for treatment or prophylaxis of neurological diseases and disorders, pain and cancer.

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Inventors:
Timianski, michael
Li, Longwen
Garman, Jonathan David
Application Number:
JP2013530433A
Publication Date:
February 01, 2017
Filing Date:
September 28, 2011
Export Citation:
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Assignee:
Nono Incorporated
International Classes:
C07K7/08; A61K38/00; A61P25/00; A61P35/00; C07K19/00; C12N15/09
Foreign References:
US7425540
WO2008025130A1
Other References:
Nat. Med., 2008, Vol. 14, No. 12, pp.1325-1332
PNAS, 2004, Vol. 101, No. 16, pp. 6237-6242
Attorney, Agent or Firm:
sk patent corporation
Akihiko Okuno
Hiroyuki Ito



 
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