Title:
フェニルメチルベンゾキノンを有効成分とするNF-κB阻害剤
Document Type and Number:
Japanese Patent JP4553413
Kind Code:
B2
Abstract:
NF-kB inhibitors containing as the active ingredient benzoquinone derivatives represented by general formula (I), hydroquinone compounds thereof or salts of the same, wherein R1, R2 and R3 independently represent each H, C1-5 alkyl or C1-5 alkoxy; R4 represents H, hydroxy-methyl, alkyl or optionally esterified or amidated carboxy; Z is represented by formula (A); and n is from 0 to 6.
Inventors:
Youichi Nunokawa
Kenji Suzuki
Masayuki Saito
Kenji Suzuki
Masayuki Saito
Application Number:
JP54807299A
Publication Date:
September 29, 2010
Filing Date:
March 19, 1999
Export Citation:
Assignee:
Matsumori Akira
International Classes:
A61K31/122; A61K31/00; A61K31/12; A61K31/165; A61K31/19; A61K31/245; A61K31/335; A61K31/36; A61K31/40; A61K31/435; A61K31/44; A61K31/445; A61K31/495; A61K31/496; A61K31/535; A61K31/5375; A61K31/54; A61K31/55; A61P29/00; A61P43/00; C07C50/28; C07C66/00; C07C235/78; C07D207/04; C07D207/08; C07D207/10; C07D211/16; C07D211/22; C07D211/32; C07D211/42; C07D211/46; C07D211/52; C07D211/58; C07D211/60; C07D211/62; C07D211/70; C07D211/74; C07D213/40; C07D213/74; C07D213/75; C07D215/08; C07D217/06; C07D223/10; C07D265/30; C07D295/18; C07D295/185; C07D317/66; C07D319/18
Domestic Patent References:
| JPH04226937A | 1992-08-17 | |||
| JPS62286949A | 1987-12-12 | |||
| JPH04226937A | 1992-08-17 | |||
| JPS62286949A | 1987-12-12 |
Other References:
JPN6009053464, Ｋｅｎｊｉ Ｓｕｚｕｋｉ ｅｔ ａｌ．, Ｃｈｅｍｉｃａｌ ＆ Ｐｈａｒｍａｃｅｕｔｉｃａｌ Ｂｕｌｌｅｔｉｎ, 1997, Ｖｏｌ． ４５， Ｎｏ． ４, ｐ． ６６８−６７４
JPN6009053466, Ｋｅｎｊｉ Ｓｕｚｕｋｉ ｅｔ ａｌ．, Ｃｈｅｍｉｃａｌ ＆ Ｐｈａｒｍａｃｅｕｔｉｃａｌ Ｂｕｌｌｅｔｉｎ, 1996, Ｖｏｌ． ４４， Ｎｏ． １, ｐ． １３９−１４４
JPN6009053466, Ｋｅｎｊｉ Ｓｕｚｕｋｉ ｅｔ ａｌ．, Ｃｈｅｍｉｃａｌ ＆ Ｐｈａｒｍａｃｅｕｔｉｃａｌ Ｂｕｌｌｅｔｉｎ, 1996, Ｖｏｌ． ４４， Ｎｏ． １, ｐ． １３９−１４４
Attorney, Agent or Firm:
Atsushi Aoki
Takashi Ishida
Fukumoto product
Tetsuji Koga
Kazuhiro Nakamura
Takashi Ishida
Fukumoto product
Tetsuji Koga
Kazuhiro Nakamura