Title:
親水性活性化合物のナノカプセル化
Document Type and Number:
Japanese Patent JP6533232
Kind Code:
B2
Abstract:
Provided is a nanoparticle including a water-soluble protein, a glucan and a hydrophilic active agent, the glucan being at least partially cross-linked by a metaphosphate.
Inventors:
Benita, Simon
Nasser, Tahel
Kohavi-Saudry, Riat
Nasser, Tahel
Kohavi-Saudry, Riat
Application Number:
JP2016548118A
Publication Date:
June 19, 2019
Filing Date:
January 26, 2015
Export Citation:
Assignee:
YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSTY OF JERUSALEM LTD.
International Classes:
A61K45/00; A61K9/50; A61K9/51; A61K31/70; A61K31/7088; A61K31/739; A61K38/28; A61K39/395; A61K47/32; A61K47/34; A61K47/36; A61K47/38; A61K47/42; A61K49/00
Domestic Patent References:
| JP2013537206A | ||||
| JP2012506900A | ||||
| JP2003501217A |
Foreign References:
| WO2013042125A1 |
Other References:
WOITISKI C. B. et al.,Pharmacological effect of orally delivered insulin facilitated by multilayered stable nanoparticle,European Journal of Pharmaceutical Sciences,2010年,VOL. 41, ISSUE 3-4,PP. 556-563
CHALASANI K. B. et al.,Effective oral delivery of insulin in animal models using vitamin B12-coated dextran nanoparticles,Journal of Controlled Release,2007年,VOL. 122, ISSUE 2,PP. 141-150
岩波 理化学事典 第5版,2006年 9月 5日,第5版第9刷,第584頁
CHALASANI K. B. et al.,Effective oral delivery of insulin in animal models using vitamin B12-coated dextran nanoparticles,Journal of Controlled Release,2007年,VOL. 122, ISSUE 2,PP. 141-150
岩波 理化学事典 第5版,2006年 9月 5日,第5版第9刷,第584頁
Attorney, Agent or Firm:
Patent business corporation Kita Aoyama International