Title:
表面安定剤として共重合体を含むナノ粒子組成物
Document Type and Number:
Japanese Patent JP4541647
Kind Code:
B2
Abstract:
The present invention is directed to nanoparticulate compositions comprising a poorly soluble drug and at least one copolymer of vinyl pyrrolidone and vinyl acetate as a surface stabilizer adsorbed to the surface of the drug. Also encompassed by the invention are pharmaceutical compositions comprising a nanoparticulate composition of the invention, methods of making and using such nanoparticulate and pharmaceutical compositions.
Inventors:
Bosch henry william
Ride Neal Speed.
Ride Neal Speed.
Application Number:
JP2002590934A
Publication Date:
September 08, 2010
Filing Date:
November 16, 2001
Export Citation:
Assignee:
Elan Pharma International, Limited
International Classes:
A61K9/14; A61K9/51; A61K31/192; A61K31/4422; A61K31/573; A61K38/00; A61K45/00; A61K47/04; A61K47/10; A61K47/12; A61K47/14; A61K47/18; A61K47/24; A61K47/26; A61K47/30; A61K47/32; A61K47/34; A61K47/42; A61K49/04; A61P9/10; A61P9/12; A61P29/00; A61P37/08
Domestic Patent References:
| JP10067758A | ||||
| JP63240936A | ||||
| JP6292825A | ||||
| JP7503003A | ||||
| JP2004513886A | ||||
| JP6211646A | ||||
| JP6192131A | ||||
| JP2000516244A | ||||
| JP2001509518A |
Foreign References:
| WO2000018374A1 |
Other References:
S.T.P. PHARMA SCIENCES,1992年,Vol.2,No.2,pp.186-192
Pharmaceutical Research,1999年,Vol.16,No.11,pp.1722-1728
European Journal of Pharmaceutics and Biopharmaceutics,2000年,Vol.49,No.3,pp.237-242
Labo-Pharma Probl. Tech.,Vol.32,No.348,pp.835-837
Journal of Microencapsulation,1993年,Vol.10,No.1,pp.89-99
Pharmaceutical Research,1999年,Vol.16,No.11,pp.1722-1728
European Journal of Pharmaceutics and Biopharmaceutics,2000年,Vol.49,No.3,pp.237-242
Labo-Pharma Probl. Tech.,Vol.32,No.348,pp.835-837
Journal of Microencapsulation,1993年,Vol.10,No.1,pp.89-99
Attorney, Agent or Firm:
Hatsushi Shimizu
Toshi Gobe
Koichi Niimi
Tomohiko Kobayashi
Shinichi Watanabe
Ryuichi Inoue
Masato Ozeki
Toshi Gobe
Koichi Niimi
Tomohiko Kobayashi
Shinichi Watanabe
Ryuichi Inoue
Masato Ozeki