タキサンを含有するナノ粒子およびその使用

Title:

タキサンを含有するナノ粒子およびその使用

Document Type and Number:

Japanese Patent JP6661700

Kind Code:

B2

Abstract:

The present invention is related to an aggregate for use in the treatment of cancer, wherein the aggregate comprisesa) a polyoxazoline comprising at least one terminal group modified with a hydrophobic moiety, wherein said polyoxazoline further comprises a linear portion, a branched portion or both, and said branched portion comprises a symmetrically branched polymer, an asymmetrically branched polymer or a combination thereof; wherein said polyoxazoline comprises a ratio of monomer to initiator is 60:1,b) a taxane, wherein said polyoxazoline and said taxane has a weight ratio of polymer to taxane of 2:1 to 10:1, andc) a size from 50 nm to about 100 nm before lyophilization.

More Like This:

JP7284097	drug delivery system
WO/2006/088676	METHOD OF MODULATING DRUG RELEASE FROM A COATED SUBSTRATE
JP2003508447	INDUSTRIAL APPLICABILITY Dosage for treatment with anti-ErbB2 antibody

Inventors:

Inn, Ray
Bread gin
Chan, Ubay
Butterfly, vince
Yen, Yun

Application Number:

JP2018115890A

Publication Date:

March 11, 2020

Filing Date:

June 19, 2018

Export Citation:

Click for automatic bibliography generation Help