To provide a new compound useful as a tyrosine phosphatase inhibitor, a tyrosine phosphatase inhibitor, a medicinal composition, a cell proliferation inhibitor, a cell-cycle progress inhibitor, an antibacterial agent, an imipenem activity promoter and a bacterial cell proliferation inhibitor containing the compound as an active component, an imipenem activity promotion method and bacterial cell proliferation inhibiting method using the compound, an activity promoting agent for the compound and an activity promoting method.
The naphthoquinone derivative compound or its pharmacologically permissible salt has a tyrosine phosphatase inhibiting activity, cell proliferation inhibiting activity, a cell-cycle progress inhibiting activity, an antibacterial activity, an activity to promote imipenem action and bacterial cell proliferation inhibiting activity. Imipenem has an action to promote the activity of naphthoquinone derivative compounds and their pharmacologically permissible salts.
IMOTO MASAYA
SHINBASHI AKIKO
TSUCHIYA AYAKO
KODA HIROSHI
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