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Title:
NATURAL COMBINATION HORMONE REPLACEMENT THERAPY AGENTS AND THERAPIES
Document Type and Number:
Japanese Patent JP2018024688
Kind Code:
A
Abstract:
PROBLEM TO BE SOLVED: To provide natural combination hormone replacement therapy agents.SOLUTION: Estrogen and progesterone replacement therapies are provided herein. Among others, the following formulations are provided herein: solubilized estradiol without progesterone; micronized progesterone without estradiol; micronized progesterone without partially solubilized progesterone; solubilized estradiol with micronized progesterone; solubilized estradiol with micronized progesterone in combination with partially solubilized progesterone; and solubilized estradiol with solubilized progesterone.SELECTED DRAWING: Figure 5

Inventors:
BRIAN A BERNICK
JANICE LOUISE CACACE
PETER H R PERSICANER
NEDA IRANI
JULIA M AMADIO
Application Number:
JP2017176379A
Publication Date:
February 15, 2018
Filing Date:
September 14, 2017
Export Citation:
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Assignee:
THERAPEUTICSMD INC
International Classes:
A61K31/565; A61K9/06; A61K9/20; A61K31/57; A61K47/14; A61K47/34; A61K47/44; A61P15/00; A61P43/00
Domestic Patent References:
JP2000510458A2000-08-15
JPH10503750A1998-04-07
Foreign References:
US4900734A1990-02-13
US20110312928A12011-12-22
US20030077297A12003-04-24
WO2003077923A12003-09-25
US6294192B12001-09-25
US20100136105A12010-06-03
US20090318558A12009-12-24
Attorney, Agent or Firm:
Kenji Sugimura
Tsukanaka Tetsuo