Title:
組織形成因子誘導による神経の再生と修復
Document Type and Number:
Japanese Patent JP4344012
Kind Code:
B2
Abstract:
Disclosed are therapeutic treatment methods, compositions and devices for maintaining neural pathways in a mammal, including enhancing survival of neurons at risk of dying, inducing cellular repair of damaged neurons and neural pathways, and stimulating neurons to maintain their differentiated phenotype. In one embodiment, the invention provides means for stimulating CAM expression in neurons. The invention also provides means for evaluating the status of nerve tissue, including means for detecting and monitoring neuropathies in a mammal. The methods, devices and compositions include a morphogen-stimulating agent provided to the mammal in a therapeutically effective concentration.
Inventors:
Luger, Divid Sea.
Kuvera Sampass, Sangebel
Herman, Opperman
Ozkinak, engine
Pang, Roy Et.
Cohen, Charles M.
Kuvera Sampass, Sangebel
Herman, Opperman
Ozkinak, engine
Pang, Roy Et.
Cohen, Charles M.
Application Number:
JP50548594A
Publication Date:
October 14, 2009
Filing Date:
July 29, 1993
Export Citation:
Assignee:
STRYKER CORPORATION
International Classes:
A61K38/00; G01N33/50; A61K6/00; A61K38/18; A61L27/22; A61L27/24; A61P25/00; A61P25/02; A61P25/14; A61P25/16; A61P25/28; A61P25/32; A61P35/00; A61P43/00; C07K14/435; C07K14/47; C07K14/495; C07K14/51; C07K16/22; C12Q1/06; G01N33/53; G01N33/68; A61F2/00; A61K48/00
Foreign References:
| WO1992000382A1 |
Other References:
Development,1991,VOL.111,No.2,pp.531-542
Attorney, Agent or Firm:
Kiyoshi Fujino