Title:
ランゲルハンス細胞活性化作用を呈するノイラミン酸誘導体及びその製造方法
Document Type and Number:
Japanese Patent JP6751838
Kind Code:
B2
Abstract:
PROBLEM TO BE SOLVED: To provide a neuraminic acid derivative exhibiting Langerhans cell-activating action and a method for producing the same.SOLUTION: According to the invention, a neuraminic acid derivative of interest is a derivative consisting of one molecule of neuraminic acid and one molecule of glutamine, which are bound by a peptidic linkage. A method for producing such a derivative consists of the steps of adding branched cyclodextrin to a fermentation broth in which Morchella esculenta and soybean are fermented with Bacillus natto. Here, the neuraminic acid derivative can also be used for health foods, cosmetics, medicines, and quasi-drugs for the purpose of immunomodulation, anti-allergy, skin-beautifying action, measures against atopy, and antioxidant action by generation of hydrogen gas. A synergistic action with EGF is also recognized.SELECTED DRAWING: None
Inventors:
Yoshimura Nimura
Application Number:
JP2016024629A
Publication Date:
September 09, 2020
Filing Date:
February 12, 2016
Export Citation:
Assignee:
Yuji Kobayashi
International Classes:
C12P19/00; A61K31/7012; A61P37/02; A61P37/04; A61P43/00; C07H7/02; C12N5/077
Domestic Patent References:
| JP2010059201A | ||||
| JP4094662B2 | ||||
| JP3151398A |