Title:
神経保護方法、組成物、およびそのスクリーニング法
Document Type and Number:
Japanese Patent JP2005521707
Kind Code:
A
Abstract:
The present invention relates in general to methods of protecting a mammalian central nervous system cell from damage, and to methods of treating or ameliorating neurodegenerative diseases. The invention further relates to screening for neuro-protective agents that may alone, or in combination with other neuroprotective agents, aid in protecting cells of the central nervous system from damage attributed to neurotoxic compounds, free radicals, or neurodegenerative diseases. The invention further relates to pharmaceutical compositions comprising L-ergothioneine or other newly identified compounds and pharmaceutically acceptable carriers for administration to a mammal in need of neuroprotection.
Inventors:
Al Oma, Okeye.
Application Number:
JP2003579759A
Publication Date:
July 21, 2005
Filing Date:
March 28, 2003
Export Citation:
Assignee:
Oxys International, Inc.
International Classes:
G01N33/50; A61K31/122; A61K31/19; A61K31/198; A61K31/34; A61K31/355; A61K31/375; A61K31/4045; A61K31/415; A61K31/4164; A61K31/4172; A61K31/4196; A61K31/455; A61K31/7088; A61K38/00; A61K45/06; A61P21/02; A61P25/00; A61P25/16; A61P25/28; A61P27/02; A61P31/18; C07D233/84; C12Q1/02; G01N33/15; (IPC1-7): A61K31/4172; A61K31/122; A61K31/19; A61K31/198; A61K31/355; A61K31/375; A61K31/4045; A61K31/4196; A61K31/455; A61K31/7088; A61K38/00; A61P21/02; A61P25/00; A61P25/16; A61P25/28; A61P27/02; A61P31/18; C07D233/84; C12Q1/02; G01N33/15; G01N33/50
Attorney, Agent or Firm:
Hidesaku Yamamoto
Takaaki Yasumura
Natsuki Morishita
Takaaki Yasumura
Natsuki Morishita