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Title:
中和プロラクチン受容体抗体およびそれらの治療的使用
Document Type and Number:
Japanese Patent JP2013513363
Kind Code:
A
Abstract:
SUMMARY The present invention is directed to the use of neutralizing prolactin receptor antibodies and antigen binding fragments thereof in combined hormone therapy.

Inventors:
Christiane Otto
Sigmund Wolf
Christoph Freiberg
Axel harenga
Simone Greven
Marc Troutwein
Sandra Bruder
Application Number:
JP2012542434A
Publication Date:
April 22, 2013
Filing Date:
November 18, 2010
Export Citation:
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Assignee:
Bayer Intellectual Property GmbH
International Classes:
C12N15/09; A61K38/22; A61K39/395; A61P13/08; A61P15/08; A61P15/14; A61P15/18; A61P17/14; A61P43/00; C07K16/28; C12N1/15; C12N1/19; C12N5/10; C12P21/02; C12P21/08
Domestic Patent References:
JP2013513362A2013-04-22
JP2013513364A2013-04-22
Foreign References:
WO2008022295A22008-02-21
EP2025683A12009-02-18
Other References:
JPN5013001238; MARTINEZ L.B. et al: 'PROLACTIN RECEPTOR IN HUMAN ENDOMETRIOTIC TISSUES' ACTA OBSTETRICIA AND GYNECOLOGICA SCANDINAVICA Vol. 81, No. 1, 2002, p. 5-10, MUNKSGAARD
JPN5013001239; BOHNET H.G. et al: 'IN VIVO EFFECTS OF ANTISERA TO PROLACTIN RECEPTORS IN FEMALE RATS' ENDOCRINOLOGY Vol. 102, No. 6, 1978, p. 1657-1661
JPN5013001240; SISSOM J.F. et al: AMERICAN JOURNAL OF PATHOLOGY Vol. 133, No. 3, 198812, p. 589-595, AMERICAN SOCIETY FOR INVESTIGATIVE PATHOLOGY
JPN5013001241; FOITZIK K.: AKT DERMATOL Vol. 31, 2005, p. 109-116, GEORG THIEME VERLAG
Attorney, Agent or Firm:
Mitsuo Tanaka
Hiroshi Yamazaki
Kenji Tomita
Mina Shiga