Title:
新規なCXCR2阻害剤
Document Type and Number:
Japanese Patent JP5237938
Kind Code:
B2
Abstract:
The invention relates to compounds of the formula I in which R1, R2, X, A, B, Z and Y1 to Y4 have the meanings indicated in the claims, and/or a pharmaceutically acceptable salt and/or a prodrug thereof. Because of their properties as inhibitors of chemokine receptors, especially as CXCR2 inhibitors, the compounds of the formula I and the pharmaceutically acceptable salts and prodrugs thereof are suitable for the prevention and treatment of chemokine mediated diseases.
Inventors:
Stephanie Hachtel
Ürgen dedio
Elizabeth Defosa
Sven Grueneberg
Holger Haiti
William Bock
Charlie Chen
Raymond Cosley
Chun-Yee Kung
Marcel Patek
Rosie Share
Stephen Simshock
Alexandra Wixell
Ürgen dedio
Elizabeth Defosa
Sven Grueneberg
Holger Haiti
William Bock
Charlie Chen
Raymond Cosley
Chun-Yee Kung
Marcel Patek
Rosie Share
Stephen Simshock
Alexandra Wixell
Application Number:
JP2009516959A
Publication Date:
July 17, 2013
Filing Date:
June 25, 2007
Export Citation:
Assignee:
SANOFI
International Classes:
C07C235/66; A61K31/198; A61K31/381; A61K31/382; A61K31/4164; A61K31/4402; A61K31/4409; A61K31/4453; A61K31/47; A61P1/02; A61P1/04; A61P1/16; A61P1/18; A61P7/00; A61P7/02; A61P9/00; A61P9/08; A61P9/10; A61P9/12; A61P9/14; A61P11/00; A61P11/06; A61P11/10; A61P11/14; A61P13/12; A61P15/06; A61P17/00; A61P17/02; A61P17/04; A61P17/06; A61P19/02; A61P19/06; A61P19/10; A61P21/00; A61P25/00; A61P25/06; A61P25/28; A61P27/02; A61P27/16; A61P29/00; A61P31/04; A61P31/12; A61P31/18; A61P31/22; A61P33/06; A61P35/00; A61P35/04; A61P37/04; A61P37/06; A61P37/08; A61P39/02; A61P39/06; A61P43/00; C07C233/83; C07C237/48; C07C311/29; C07D213/30; C07D233/60; C07D295/08; C07D333/16; C07D333/38; C07D333/70; C07D335/02
Domestic Patent References:
| JP2008526695A |
Attorney, Agent or Firm:
Junji Yuda
Shoji Miwa
Noriyuki Takebayashi
Chika Takagi
Shoji Miwa
Noriyuki Takebayashi
Chika Takagi