Title:
新規FKI-3864物質およびその製造方法
Document Type and Number:
Japanese Patent JP5163168
Kind Code:
B2
Abstract:
This invention relates to substance FKI-3864 represented by the following formula [I] having an inhibitory activity on the synthesis of triacylglycerols and a method for preparing the same. The substance FKI-3864 can be prepared by a method comprising culturing a microorganism which belongs to the genus Penicillium and is capable of producing the substance FKI-3864, and particularly Penicillium pinophilum FKI-3864 (FERM BP-11093) so as to accumulate the substance FKI-3864 in the culture and collecting the substance FKI-3864 from the culture. The substance has an inhibitory activity on the synthesis of intracellular triacylglycerols and is useful for prevention or treatment of obesity.
Inventors:
Hiroshi Donada
Ryuji Uchida
Ikuro Masuma
Satoshi Omura
Ryuji Uchida
Ikuro Masuma
Satoshi Omura
Application Number:
JP2008032172A
Publication Date:
March 13, 2013
Filing Date:
February 13, 2008
Export Citation:
Assignee:
Kitasato Institute
International Classes:
C07D311/92; A61K31/366; A61P3/04; A61P43/00; C12N1/14; C12P17/06; A61P3/06; A61P3/10; A61P9/12; C12R1/80
Domestic Patent References:
| JP8182496A |
Foreign References:
| WO2000058491A1 | ||||
| WO1999041265A1 |
Attorney, Agent or Firm:
Shoichi Hirose