新規のGLP-1受容体安定化薬および調節薬

Japanese Patent JP2013530963

A

Compounds that bind the glucagon-like peptide 1 receptor (GLP-1) receptor are provided including compounds which are modulators of the GLP-1 receptors and compounds which are capable of inducing a stabilizing effect on the receptor for use in structural analysis of the GLP-1 receptor. Methods of synthesis, methods of therapeutic and/or prophylactic use, and methods of use in stabilizing GLP-1 receptor in vitro for crystallization of the GLP-1 receptor of such compounds are provided.

Baume, Marcus F.
Martinborough, Esta
Mujani, Manisha
Fan, lee min
Junko Tamiya
Griffith, Mark Tee.
Fowler, thomas
Andrew, Novac
Michael Naggs
Megani, Premuzi

JP2013514378A

August 01, 2013

June 09, 2011

Click for automatic bibliography generation  

RECEPTOS, INC.

C07C233/87; A61K31/235; A61K31/341; A61K31/343; A61K31/351; A61K31/36; A61K31/381; A61K31/40; A61K31/401; A61K31/415; A61K31/4164; A61K31/42; A61K31/421; A61K31/4245; A61K31/426; A61K31/428; A61K31/433; A61K31/437; A61K31/4402; A61K31/4406; A61K31/4409; A61K31/445; A61K31/451; A61K31/455; A61K31/47; A61K31/498; A61K31/4985; A61K38/00; A61K45/00; A61P3/00; A61P3/04; A61P3/10; A61P43/00; C07C235/52; C07C237/42; C07C255/57; C07C311/13; C07C311/21; C07C317/24; C07C321/28; C07D207/34; C07D211/62; C07D213/55; C07D213/56; C07D213/81; C07D213/82; C07D215/48; C07D231/14; C07D233/90; C07D241/44; C07D261/18; C07D261/20; C07D263/34; C07D271/10; C07D277/20; C07D277/56; C07D277/62; C07D285/14; C07D295/14; C07D307/54; C07D307/68; C07D307/81; C07D307/85; C07D309/08; C07D317/60; C07D333/24; C07D333/38; C07D333/70; C07D471/04; C07K14/575

Hidesaku Yamamoto
Kensaku Yamamoto
Natsuki Morishita
Takatoshi Iida
Daisuke Ishikawa

Previous Patent: シクロペンテン組成物

Next Patent: 方法