Title:
生体分子を接合するための新規な試薬及び方法
Document Type and Number:
Japanese Patent JP5622117
Kind Code:
B2
Abstract:
The invention relates to a process for the conjugation of a molecule containing a thiol or amino group to a polymer, which comprises reacting said molecule with a compound of the general formula:
€ƒ€ƒ€ƒ€ƒ€ƒ€ƒ€ƒ€ƒ X-[Q-W-(CH=CH) n -CH=CH 2 ] m €ƒ€ƒ€ƒ€ƒ€ƒ(V)
in which X represents a polymer; Q represents a linking group; W represents a keto group or an ester group -O-CO-; n represents 0 or an integer of from 1 to 4; and m represent an integer of from 1 to 8. The invention also relates to a compound of the general formula
€ƒ€ƒ€ƒ€ƒ€ƒ€ƒ€ƒ€ƒ X-[NH-CO-Ar-W-(CH=CH) n -CH=CH 2 ] m €ƒ€ƒ€ƒ€ƒ€ƒ(Va)
in which X, W, n and m have the meanings given above; and Ar represents an unsubstituted or substituted aryl group.
Inventors:
ゴドウィン，アンソニー
Application Number:
JP2011519228A
Publication Date:
November 12, 2014
Filing Date:
July 17, 2009
Export Citation:
Assignee:
ポリテリクスリミテッド
International Classes:
A61K47/48; A61K47/32; A61K47/34; A61K47/36; A61K47/42; C08F8/00; C08G65/00; C08G85/00
Attorney, Agent or Firm:
Sepal Tsuneo
Yoshio Miyazaki
Tsutomu Kato
Kyoko Koyama
伴 Tomoatsu
Yoshio Miyazaki
Tsutomu Kato
Kyoko Koyama
伴 Tomoatsu