Title:
新規アミドおよびアミジン誘導体ならびにこれらの使用
Document Type and Number:
Japanese Patent JP2012524121
Kind Code:
A
Abstract:
The present invention relates to inhibitors of 11- ß-hydroxysteroid dehydrogenase type 1 enzyme and their use in treatment of non-insulin dependent type 2 diabetes, insulin resistance, obesity, lipid disorders, metabolic syndrome, central nervous system disorders, and diseases and conditions that are related to excessive glucocorticoids.
Inventors:
Pedi, Siridard
Patel, Mina Buoy
Lord, jeffrey jei
Patel, Mina Buoy
Lord, jeffrey jei
Application Number:
JP2012507294A
Publication Date:
October 11, 2012
Filing Date:
April 20, 2010
Export Citation:
Assignee:
ABBOTT LABORATORIES
International Classes:
C07C327/42; A61K31/155; A61K31/16; A61K31/165; A61K31/216; A61K31/275; A61K31/351; A61K31/36; A61K31/381; A61K31/395; A61K31/397; A61K31/40; A61K31/403; A61K31/4035; A61K31/4045; A61K31/407; A61K31/41; A61K31/415; A61K31/4155; A61K31/4196; A61K31/42; A61K31/4245; A61K31/426; A61K31/428; A61K31/429; A61K31/438; A61K31/439; A61K31/44; A61K31/4402; A61K31/4439; A61K31/445; A61K31/4535; A61K31/454; A61K31/455; A61K31/46; A61K31/47; A61K31/495; A61K31/496; A61K31/498; A61K31/501; A61K31/506; A61K31/5375; A61K31/5377; A61K31/55; A61K31/551; A61P1/18; A61P3/04; A61P3/06; A61P3/10; A61P9/00; A61P9/10; A61P9/12; A61P13/12; A61P19/00; A61P19/10; A61P25/00; A61P25/18; A61P25/22; A61P25/24; A61P25/28; A61P27/02; A61P27/06; A61P43/00; C07C257/14; C07C259/14; C07C261/04; C07D205/04; C07D207/06; C07D207/08; C07D207/09; C07D207/10; C07D207/12; C07D207/14; C07D207/26; C07D209/14; C07D209/44; C07D209/52; C07D211/26; C07D211/38; C07D211/40; C07D211/42; C07D211/58; C07D211/60; C07D213/30; C07D213/58; C07D213/61; C07D213/64; C07D213/70; C07D213/74; C07D213/84; C07D213/85; C07D215/14; C07D223/16; C07D231/06; C07D231/08; C07D231/12; C07D231/16; C07D231/20; C07D239/42; C07D241/20; C07D241/42; C07D243/06; C07D243/08; C07D245/02; C07D257/04; C07D261/08; C07D261/12; C07D265/30; C07D271/06; C07D277/20; C07D277/28; C07D277/42; C07D277/82; C07D295/08; C07D295/12; C07D295/20; C07D295/22; C07D307/22; C07D309/06; C07D317/64; C07D333/20; C07D333/58; C07D401/04; C07D401/12; C07D401/14; C07D403/04; C07D403/12; C07D409/12; C07D413/04; C07D413/14; C07D417/12; C07D451/06; C07D453/02; C07D471/08; C07D471/10; C07D471/18; C07D487/04; C07D487/08; C07D487/10; C07D491/056; C07D491/08; C07D498/10
Domestic Patent References:
| JP2004523496A | 2004-08-05 | |||
| JPS562957A | 1981-01-13 | |||
| JP2009046464A | 2009-03-05 | |||
| JP2008526874A | 2008-07-24 |
Foreign References:
| US2450386A | 1948-09-28 | |||
| US4156014A | 1979-05-22 | |||
| WO1992004054A1 | 1992-03-19 | |||
| GB1306139A | 1973-02-07 | |||
| CA1157774A | 1983-11-29 | |||
| US4196299A | 1980-04-01 |
Other References:
J. CHEM. SOC. PERKIN TRANS. 1, JPN7014001197, 1997, pages 2319 - 2327, ISSN: 0002793595
JOURNAL OF PLANAR CHROMATOGRAPHY, vol. 2, no. 2, JPN7014001198, 1989, pages 163 - 164, ISSN: 0002793596
DATABASE CAPLUS [ONLINE]: CHEMICAL ABSTRACTS SERVICE, COLUMBUS, OHIO, USA. RETRIEVED FROM STN, JPN7014001199, pages 2005 - 951697, ISSN: 0002793597
DATABASE CAPLUS [ONLINE]: CHEMICAL ABSTRACTS SERVICE, COLUMBUS, OHIO, USA. RETRIEVED FROM STN, JPN7014001201, pages 1978 - 6370, ISSN: 0002793598
DATABASE CAPLUS [ONLINE]: CHEMICAL ABSTRACTS SERVICE, COLUMBUS, OHIO, USA. RETRIEVED FROM STN, JPN7014001202, pages 1987 - 119589, ISSN: 0002793599
DATABASE CAPLUS [ONLINE]: CHEMICAL ABSTRACTS SERVICE, COLUMBUS, OHIO, USA. RETRIEVED FROM STN, JPN7014001195, pages 1974 - 44021, ISSN: 0002793593
JOURNAL OF MEDICINAL CHEMISTRY, vol. 22, no. 3, JPN7014001196, 1979, pages 295 - 301, ISSN: 0002793594
JOURNAL OF PLANAR CHROMATOGRAPHY, vol. 2, no. 2, JPN7014001198, 1989, pages 163 - 164, ISSN: 0002793596
DATABASE CAPLUS [ONLINE]: CHEMICAL ABSTRACTS SERVICE, COLUMBUS, OHIO, USA. RETRIEVED FROM STN, JPN7014001199, pages 2005 - 951697, ISSN: 0002793597
DATABASE CAPLUS [ONLINE]: CHEMICAL ABSTRACTS SERVICE, COLUMBUS, OHIO, USA. RETRIEVED FROM STN, JPN7014001201, pages 1978 - 6370, ISSN: 0002793598
DATABASE CAPLUS [ONLINE]: CHEMICAL ABSTRACTS SERVICE, COLUMBUS, OHIO, USA. RETRIEVED FROM STN, JPN7014001202, pages 1987 - 119589, ISSN: 0002793599
DATABASE CAPLUS [ONLINE]: CHEMICAL ABSTRACTS SERVICE, COLUMBUS, OHIO, USA. RETRIEVED FROM STN, JPN7014001195, pages 1974 - 44021, ISSN: 0002793593
JOURNAL OF MEDICINAL CHEMISTRY, vol. 22, no. 3, JPN7014001196, 1979, pages 295 - 301, ISSN: 0002793594
Attorney, Agent or Firm:
Kawaguchi International Patent Office