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Patent Searching and Data


Title:
NEW ANTIBIOTIC SF2738 SUBSTANCE, ITS PRODUCTION AND CARCINOSTATIC AGENT
Document Type and Number:
Japanese Patent JPH0578322
Kind Code:
A
Abstract:

PURPOSE: To obtain a new antitumor antibiotic SF2,738 substance useful as a carcinostatic agent and its salt.

CONSTITUTION: An antitumor substance SF2,7838 substance of the formula or its salt. The compound is obtained by culturing a bacterium such as Streptomyces sp. SF2,738 strain (FERM P-12,494) belonging to the genus Streptomyces, capable of producing antibiotic SF2,738 substance, in a medium containing nutritive substances usable for common bacteria and isolating the antibiotic SF2,738 substance from the culture mixture by solvent extraction method or silica gel chromatography method. The compound can be orally or parenterally administered as an active ingredient of a carcinostatic agent and its daily dose is preferably 5-100mg based on 1kg body weight of mammal including human.


Inventors:
GOMI SHUICHI
ITO OSAMU
AJITO YOSHIYO
AMANO SHOICHI
SATOU ERIKO
KARIYA HIROKO
KOYAMA MASAO
Application Number:
JP24133291A
Publication Date:
March 30, 1993
Filing Date:
September 20, 1991
Export Citation:
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Assignee:
MEIJI SEIKA KAISHA
International Classes:
A61K31/44; A61K31/4402; A61K31/4418; A61P35/00; C07D213/70; C12P17/12; C12R1/465; (IPC1-7): A61K31/44; C07D213/70; C12P17/12