Title:
新規なベキサロテンアナログ
Document Type and Number:
Japanese Patent JP5784045
Kind Code:
B2
Abstract:
The present invention relates to analogs of bexarotene and methods of use thereof.
Inventors:
Wagner, Karl E.
Jultska, Peter W..
Marshall, Pamela A.
Van der Vaart, Aryan
Jultska, Peter W..
Marshall, Pamela A.
Van der Vaart, Aryan
Application Number:
JP2012554030A
Publication Date:
September 24, 2015
Filing Date:
February 17, 2011
Export Citation:
Assignee:
Arizona Board of Regents, A Body Corporate of the State of Arizona, Acting for and on Behalf of Arizona State University
International Classes:
C07C63/74; A61K31/192; A61P35/00
Domestic Patent References:
| JP8505852A | ||||
| JP11503472A |
Foreign References:
| WO2007022437A1 | ||||
| WO2005000233A1 |
Other References:
WAGNER,MODELING,SYNTHESIS AND BIOLOGICAL EVALUATION OF POTENTIAL RETINOID X RECEPTOR(RXR)SELECTIVE AGONISTS:NOVEL ANALOGUES OF 4-[1-(3,5,5,8,8-PENTAMETHYL-5,6,7,8-TETRAHYDRO-2-NAPHTHYL)ETHYNYL],J MED CHEM,2009年,V52,P5950-5966
Winum, Jean-Yves et al.,Synthesis of new Targretin analogues that induce apoptosis in leukemia HL-60 cells,Bioorganic & Medicinal Chemistry Letters,2002年,12(24),3529-3532
Winum, Jean-Yves et al.,Synthesis of new Targretin analogues that induce apoptosis in leukemia HL-60 cells,Bioorganic & Medicinal Chemistry Letters,2002年,12(24),3529-3532
Attorney, Agent or Firm:
Hidesaku Yamamoto
Takaaki Yasumura
Natsuki Morishita
Takaaki Yasumura
Natsuki Morishita