To obtain a new carbapenem compound having an alkenyl group and to provide a method for producing the compound.
This compound is represented by formula (1) (wherein, R1 denotes hydrogen atom or methyl group; R2 denotes hydrogen atom or a protecting group of the hydroxy group; R3 denotes hydrogen atom or a protecting group of carboxy group; R4 denotes hydrogen atom, a protecting group of amino group or a lower alkyl group; R5 and R6 denote each hydrogen atom, a protecting group of amino group or the following group (formimidoyl group, acetimidoyl group, amidino group, a lower alkanoyl group, a lower alkoxycarbonyl group, a lower alkyl group, a lower alkenyl group or an aralkyl group) which may be substituted; R7, R8 and R9 are each the same or different and denote each hydrogen atom or a 1-3C lower alkyl group which may have a substituent group or Ca, Cb, Nc, R5 and R9 together denote a nitrogen- containing saturated heterocyclic group or Cb, Nc, R5 and R7 together denote a nitrogen-containing saturated heterocyclic group) or its pharmaceutically acceptable salt.
| JP2005514323 | Method of isolating crystalline imipenem |
HASHIHAYATA TAKASHI
SAKO KOKI
SAKURABA SHUNJI
HASHIZUME TERUTAKA
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