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Title:
NEW CARBAPENEM DERIVATIVE
Document Type and Number:
Japanese Patent JP2003026679
Kind Code:
A
Abstract:

To provide a new carbapenem compound having an antimicrobial activity.

This compound is represented by formula (I) [wherein, R1 denotes hydrogen atom or methyl group; R2 denotes hydrogen atom or a protecting group of hydroxy group; R3 denotes hydrogen atom or a protecting group of carboxy group; R4 denotes hydrogen atom, a protecting group of amino group or a lower alkyl group; X is NH or a single bond; R50, R60 and R70 are each the same or different and denote each hydrogen atom, a protecting group of amino group or formimidoyl group, acetimidoyl group, amidino group, a lower alkanoyl group, a lower alkoxycarbonyl group, a lower alkyl group, a lower alkenyl group or an aralkyl group which may be substituted or Ca, R50 and R60, together with the adjacent nitrogen atom, denote a heterocyclic group represented by formula (II) (wherein, m is an integer of 1-3); and R70 denotes hydrogen atom, a protecting group of amino group or the like] or its pharmaceutically acceptable salt.


Inventors:
YAMADA KOJI
SAKURABA SHUNJI
HASHIHAYATA TAKASHI
SUGIMOTO YUICHI
IMAMURA HIDEAKI
Application Number:
JP2001209094A
Publication Date:
January 29, 2003
Filing Date:
July 10, 2001
Export Citation:
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Assignee:
BANYU PHARMA CO LTD
International Classes:
C07D477/00; A61K31/407; A61P31/04; (IPC1-7): C07D477/00; A61P31/04