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Title:
新規セファロスポリン誘導体
Document Type and Number:
Japanese Patent JP3777191
Kind Code:
B2
Abstract:
A cephalosporin derivative which has a substituted or unsubstituted 2-(5-thiazolyl)vinyl group at the 3-position and is represented by the following formula (I) wherein X is CH or N, R<1> is an amino group or a protected amino group, R<2> is a hydrogen atom or a hydroxyimino-protecting group, R<3> is a hydrogen atom, a salt-forming cation or a carboxyl-protecting group, R<4> is a hydrogen atom, and R<5> is a hydrogen atom, a lower alkyl group, a halo-(lower)alkyl group or a halogen atom, is now synthetised as a cephem compound which exhibits excellent antibacterial activities and is useful as a therapeutic agent for various bacterial infections.

Inventors:
Soujiro Shiokawa
Atsumi Kunio
Katsuyoshi Iwamatsu
Atsushi Tamura
Seiji Shibahara
Application Number:
JP51022095A
Publication Date:
May 24, 2006
Filing Date:
September 29, 1994
Export Citation:
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Assignee:
Meiji Seika Co., Ltd.
International Classes:
C07D501/24; A61K31/04; A61K31/545; C07D501/00
Domestic Patent References:
JP3264590A
JP62205088A
Attorney, Agent or Firm:
Takao Hamano
Morita Tetsuji