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Title:
NEW CHLOROUS ACID DISMUTASE DERIVED FROM HIGHLY THERMOPHILIC BACTERIUM AND USE OF THREE-DIMENSIONAL STRUCTURE OF THE SAME
Document Type and Number:
Japanese Patent JP2005058223
Kind Code:
A
Abstract:

To find out a new protein useful as a heat-resistant enzyme, by analyzing a three-dimensional structure of a hypothetical protein obtained from a genomic analysis of a highly thermophilic bacterium and clarifying a function characterized by the structure.

A new chlorous acid dismutase having a specific amino acid sequence and base sequence and a gene thereof are provided, respectively. Further, an enzyme modifying method for changing substrate specificity of the enzyme and/or improving specific activity thereof based on the three-dimensional structure of the chlorous acid dismutase and the chlorous acid dismutase of variant type which is modified by the method are provided, respectively.


Inventors:
Ebihara, Akio
Okamoto, Akihiro
Kokaku, Yukihide
Kuramitsu, Shigenori
Yokoyama, Shigeyuki
Application Number:
JP2004000219764
Publication Date:
March 10, 2005
Filing Date:
July 28, 2004
Export Citation:
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Assignee:
INSTITUTE OF PHYSICAL & CHEMICAL RESEARCH
International Classes:
C12N15/09; C12N1/15; C12N1/19; C12N1/21; C12N5/10; C12N9/02; C12P3/00; (IPC1-7): C12N15/09; C12N1/15; C12N1/19; C12N1/21; C12N5/10; C12N9/02; C12P3/00