Title:
新規合成クリプトフィシン類
Document Type and Number:
Japanese Patent JP4181632
Kind Code:
B2
Abstract:
Novel cryptophycin compounds are disclosed, together with methods of producing cryptophycins by total synthesis and methods for the use of such cryptophycins in pharmaceuticals to inhibit the proliferation of mammalian cells and to treat neoplasia.
Inventors:
Moa, richard, y
Tius, Marcus, A
Barrow, Russell, A
Lian, Gian
Corbett, Thomas, H
Ballariot, Frederick, A
Hemscheid, Thomas, Kay
Gorakoti, Trimrutal
Tius, Marcus, A
Barrow, Russell, A
Lian, Gian
Corbett, Thomas, H
Ballariot, Frederick, A
Hemscheid, Thomas, Kay
Gorakoti, Trimrutal
Application Number:
JP50044097A
Publication Date:
November 19, 2008
Filing Date:
March 07, 1996
Export Citation:
Assignee:
University of Hawaii
Wayne State University
Wayne State University
International Classes:
C07D273/00; A61K31/00; C07D307/20; A61K31/34; A61K31/341; A61K31/395; A61K38/00; A61P1/00; A61P5/00; A61P11/00; A61P13/00; A61P13/08; A61P15/00; A61P25/14; A61P35/00; A61P35/02; A61P43/00; C07C231/02; C07C237/22; C07D257/02; C07D273/08; C07D407/06; C07D409/04; C07K5/12
Domestic Patent References:
| JP8092232A |
Foreign References:
| US4946835 | ||||
| US4845085 | ||||
| US4845086 |
Other References:
SMITH, C.D. et al., Cancer Research, 1994年 7月15日, Vol.54/No.14, p.3779-3784
TRIMURTULU, G. et al., J. Am. Chem. Soc., 米国, 1994年, Vol.116/No.11, p.4729-4737
TRIMURTULU, G. et al., 天然有機化合物討論会講演要旨集, 日本, 1994年, 36th, p.744-751
KOBAYASHI, M. et al., Chem. Pharm. Bull., 日本, 1994年10月, Vol.42/No.10, p.2196-2198
KOBAYASHI, M. et al., 天然有機化合物討論会講演要旨集, 日本, 1994年, 36th, p.104-111
TRIMURTULU, G. et al., J. Am. Chem. Soc., 米国, 1994年, Vol.116/No.11, p.4729-4737
TRIMURTULU, G. et al., 天然有機化合物討論会講演要旨集, 日本, 1994年, 36th, p.744-751
KOBAYASHI, M. et al., Chem. Pharm. Bull., 日本, 1994年10月, Vol.42/No.10, p.2196-2198
KOBAYASHI, M. et al., 天然有機化合物討論会講演要旨集, 日本, 1994年, 36th, p.104-111
Attorney, Agent or Firm:
Hideto Asamura
Hajime Asamura
Yukihiro Ikeda
Naganuma Akio
Hajime Asamura
Yukihiro Ikeda
Naganuma Akio