Title:
新規化合物
Document Type and Number:
Japanese Patent JP2010519242
Kind Code:
A
Abstract:
Novel substituted amide inhibitors, their use in therapy, pharmaceutical compositions comprising the compounds, the use of said compounds in the manufacture of medicaments, and therapeutic methods comprising the administration of said compounds are described. The present compounds modulate the activity of 11β-hydroxysteroid dehydrogenase type 1 (11βHSD1) and are accordingly useful in the treatment of diseases in which such a modulation is beneficial, such as the metabolic syndrome.
Inventors:
Ebdorp, Seiren
Application Number:
JP2009550276A
Publication Date:
June 03, 2010
Filing Date:
February 19, 2008
Export Citation:
Assignee:
High Point Pharmaceuticals, Limited Liability Company
International Classes:
C07C233/74; A61K31/166; A61K31/4402; A61K31/445; A61P3/00; A61P3/04; A61P3/06; A61P3/10; A61P5/50; A61P9/12; A61P43/00; C07C235/54; C07D211/22; C07D213/30
Attorney, Agent or Firm:
Atsushi Aoki
Takashi Ishida
Fukumoto product
Tetsuji Koga
Yoichi Watanabe
Ryotaro Takei
Masaru Nakajima
Takashi Ishida
Fukumoto product
Tetsuji Koga
Yoichi Watanabe
Ryotaro Takei
Masaru Nakajima