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Title:
新規化合物
Document Type and Number:
Japanese Patent JP4209672
Kind Code:
B2
Abstract:
Pleuromutilin compounds of the formula (A) & (B) are of use in anti-bacterial therapy. in which: R 1 is optionally substituted C (1-6) alkyl or C (3-6) cycloalkyl or optionally substituted heterocyclyl; R 2 is vinyl or ethyl; R 3 is H, OH or F, and R 4 is H, or R 3 is H and R 4 is F, and R 5 and R 6 together form an oxo group; or R 3 and R 4 is each H, R 5 is OH or H and R 6 is H, or R 5 is H and R 6 is OH or H.

Inventors:
Elder, John, Stephen
Forest, andrew, keith
Javest, Richard, Lewis
Shepherd, robert, john
Application Number:
JP2002534315A
Publication Date:
January 14, 2009
Filing Date:
October 08, 2001
Export Citation:
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Assignee:
SmithKline Beecham p.l.c.
International Classes:
C07C271/66; A61K31/27; A61K31/34; A61K31/357; A61K31/38; A61K31/381; A61K31/397; A61K31/40; A61K31/4015; A61K31/415; A61K31/4178; A61K31/42; A61K31/421; A61K31/44; A61K31/4402; A61K31/4406; A61K31/4409; A61K31/4412; A61K31/445; A61K31/4462; A61K31/4465; A61K31/495; A61K31/4965; A61K31/505; A61K31/5375; A61K31/5377; A61K31/54; A61P31/04; C07C271/06; C07C311/04; C07C317/18; C07C323/12; C07D205/04; C07D207/12; C07D207/16; C07D207/22; C07D207/26; C07D207/273; C07D207/404; C07D211/00; C07D211/42; C07D211/46; C07D211/62; C07D211/76; C07D213/04; C07D213/30; C07D213/40; C07D213/64; C07D231/20; C07D231/22; C07D239/30; C07D239/42; C07D239/48; C07D239/54; C07D241/04; C07D241/24; C07D261/02; C07D261/08; C07D261/12; C07D263/24; C07D265/30; C07D279/12; C07D295/00; C07D295/185; C07D295/26; C07D307/20; C07D307/66; C07D317/10; C07D317/24; C07D319/06; C07D331/04; C07D333/32; C07D333/48; C07D401/06; C07D403/06; C07D413/06; C07D453/02; C07D493/04; C07D207/40
Domestic Patent References:
JP2000503642A
JP2003529593A
Foreign References:
WO1998005659A1
WO2001014310A1
Attorney, Agent or Firm:
Yusuke Hiraki
Ishii Teiji
Satoshi Fujita