Title:
治療的及び美容的方法に有用な新規化合物
Document Type and Number:
Japanese Patent JP2011506425
Kind Code:
A
Abstract:
The present invention relates to photosensitizer compounds for use in cosmetic and therapeutic applications of photodynamic therapy. The compounds of the present invention are designed for topical application and are characterized by a low permeability to the stratum corneum (the outer skin layer of an individual) and/or a low allergenic potential. Surprisingly, such compounds have beneficial properties in the treatment of certain diseases and lack the undesired damages to healthy skin entailed by prior art compounds. ALA (5-aminolevulinic acid)-esters of body-owned, natural compound such as aminoacids, steroids, carbohydrates, alcohols are preferred examples of photosensitizers of the present invention. The compounds of the present invention are used in the treatment of skin diseases such as psoriasis, sebaceous glands related conditions including acne, seborrhoic dermatitis, rosacea, skin cancer and precancer, as well as in cosmetic hair removal.
Inventors:
Grantsman, Thomas
Bulge, jerome
Wagner, Georges
Bulge, jerome
Wagner, Georges
Application Number:
JP2010537593A
Publication Date:
March 03, 2011
Filing Date:
December 12, 2008
Export Citation:
Assignee:
PHOTODERMA SA
International Classes:
A61K8/02; A61K8/44; A61K8/46; A61K8/49; A61K8/60; A61K8/63; A61K8/67; A61K8/96; A61K31/16; A61K31/197; A61K31/198; A61K31/22; A61K31/221; A61K31/222; A61K31/375; A61K31/5513; A61K31/575; A61K31/7028; A61K41/00; A61K45/00; A61P17/00; A61P17/06; A61P17/08; A61P17/10; A61P31/02; A61P31/04; A61P31/12; A61P35/00; A61Q5/00; A61Q7/02; A61Q15/00; A61Q19/00; C07C229/24; C07C229/36; C07C327/30
Domestic Patent References:
| JPH11501914A | 1999-02-16 | |||
| JP2004505105A | 2004-02-19 | |||
| JP2005501050A | 2005-01-13 | |||
| JPH1112197A | 1999-01-19 |
Foreign References:
| US20040073277A1 | 2004-04-15 | |||
| WO2006051269A1 | 2006-05-18 | |||
| US20050124984A1 | 2005-06-09 | |||
| WO2005120572A1 | 2005-12-22 |
Other References:
JPN5011001619; ＢＥＲＧＥＲ Ｙ: 'ＥＴＨＹＬＥＮＥ ＧＬＹＣＯＬ ＡＮＤ ＡＭＩＮＯ ＡＣＩＤ ＤＥＲＩＶＡＴＩＶＥＳ ＯＦ ５-ＡＭＩＮＯＬＥＶＵＬＩＮＩＣ ＡＣＩＤ 以下備考' ＪＯＵＲＮＡＬ ＯＦ ＭＥＤＩＣＩＮＡＬ ＣＨＥＭＩＳＴＲＹ , 20001201, Ｐ４７３８-４７４６, ＡＭＥＲＩＣＡＮ ＣＨＥＭＩＣＡＬ ＳＯＣＩＥＴＹ
Attorney, Agent or Firm:
Mieko Kashihara
Goichi Takahashi
Masahito Shibata
Goichi Takahashi
Masahito Shibata