Title:
NEW CRYSTALLINE CEPHEM ACID ADDITION SALT AND ITS PREPARATION
Document Type and Number:
Japanese Patent JP3920939
Kind Code:
B2
Abstract:
PROBLEM TO BE SOLVED: To obtain a new crystalline cephem acid addition salt with long half- life in the blood and excellent medicinal sustainability, useful for the treatment of bacterial infectious diseases.
SOLUTION: This compound is shown by formula I [(n) is 1 or 2; (m) is 0.4-2.6; X is an anion of formula II, formula III or the like], e.g. cephyquinom-6- hydroxy-1-naphthoate. The compound of formula I is obtained, for example, by reaction of cephembetaine of formula IV with a carboxylic acid of formula II or formula III.
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Inventors:
Rudolf Ratler
Walter de Jürkheimer
Peter Schmitt
Walter de Jürkheimer
Peter Schmitt
Application Number:
JP29142795A
Publication Date:
May 30, 2007
Filing Date:
November 09, 1995
Export Citation:
Assignee:
Sanofi-Aventis Deutschland Gesellschaft Mitt Beschlenktel Haftung
International Classes:
C07D501/46; A61K31/545; A61K31/546; A61P31/04; C07B63/00; C07C59/52; C07C65/03; C07C65/05; C07C65/10; C07C65/11; C07C235/52; C07D501/00; C07D501/56; (IPC1-7): C07D501/46; A61K31/545; C07B63/00; C07C59/52; C07C65/03; C07C65/05; C07C65/10; C07C65/11; C07C235/52
Domestic Patent References:
JP59130888A | ||||
JP1216995A |
Attorney, Agent or Firm:
Chika Takagi
Kosuke Nishimura
Kosuke Nishimura
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