新規なシクロヘキサン誘導体 - F. HOFFMANN-LA ROCHE AKTIENGESELLSCHAFT

Title:

新規なシクロヘキサン誘導体

Document Type and Number:

Japanese Patent JP4644714

Kind Code:

B2

Abstract:

The invention is concerned with novel hexafluoroisopropanol substituted cyclohexane derivatives of formula (I) wherein R¹to R⁴, X, m and n are as defined in the description and in the claims, as well as physiologically acceptable salts and esters thereof. These compounds bind to LXR alpha and LXR beta and can be used as medicaments.

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Inventors:

Henrietta, Damelow
Kuhn, Bernd
Raffaello, Masziadri
Panday, Narendra
Ratony, Asan
Light, matthew break

Application Number:

JP2007547283A

Publication Date:

March 02, 2011

Filing Date:

December 14, 2005

Export Citation:

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Assignee:

F. HOFFMANN-LA ROCHE AKTIENGESELLSCHAFT

International Classes:

C07C311/21; A61K31/18; A61K31/415; A61K31/4164; A61K31/426; A61P1/04; A61P1/16; A61P1/18; A61P3/06; A61P3/10; A61P9/10; A61P17/00; A61P25/28; A61P29/00; A61P31/04; A61P43/00; C07C213/08; C07C215/42; C07C229/36; C07C231/12; C07C233/23; C07C233/60; C07C233/74; C07C271/56; C07C303/40; C07C311/13; C07D231/18; C07D233/84; C07D277/20; C07D277/36

Domestic Patent References:

JP2008504313A
JP2005527621A
JP2002539155A

Foreign References:

WO2006004030A1

Attorney, Agent or Firm:

Hajime Tsukuni
Koshiro Tsukuda
Fusayuki Saito

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