Title:
NEW CYCLOPENTANE DERIVATIVES* PROCESS FOR MANUFACTURE THEREOF AND PHARMACEUTICAL COMPOSITIONS
Document Type and Number:
Japanese Patent JPS5231050
Kind Code:
A
Abstract:
Novel cyclopentanoic acid derivatives of the formula I wherein R is selected from the group consisting of and -CH2OH, R' is selected from the group consisting of hydrogen, alkyl of 1 to 4 carbon atoms and a non toxic, pharmaceutically acceptable cation and R1 is selected from the group consisting of hydrogen, 2-tetrahydropyranyl, branched or straight chain, saturated or unsaturated alkyl of 1 to 4 carbon atoms and and R2 is selected from the group consisting of straight or branched chain alkyl of 1 to 12 carbon atoms and phenyl with the alkyl and phenyl being optionally substituted with -COOA wherein A is selected from the group consisting of hydrogen, alkali metal, ammonium ion, ion of an organic amine, alkyl and haloalkyl of 1 to 7 alkyl carbon atoms with the proviso that R1 is not hydrogen or 2-tetrahydropyranyl when R is a carboxylic group, and the OH and R groups on the ring and OR1 group on the chain may be in either of the two possible positions about the carbon atom to which they are attached having analgesic, anti-inflammatory and smooth muscle relaxant activity.
More Like This:
Inventors:
JIYAN BIYUANDEIA
MISHIERU BIBA
JIYANIINU SHIYARUBAARU
MISHIERU BIBA
JIYANIINU SHIYARUBAARU
Application Number:
JP10177776A
Publication Date:
March 09, 1977
Filing Date:
August 27, 1976
Export Citation:
Assignee:
ROUSSEL UCLAF
International Classes:
A61K31/045; A61K31/19; A61P43/00; C07C35/06; C07C67/00; C07C401/00; C07C405/00; (IPC1-7): A61K31/045; A61K31/19; C07C177/00