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Title:
医学的治療のための新規の金系ナノ結晶、及び該金系ナノ結晶のための電気化学的製造方法
Document Type and Number:
Japanese Patent JP6703052
Kind Code:
B2
Abstract:
The present invention relates to novel gold nanocrystals and nanocrystal shape distributions that have surfaces that are substantially free from organic impurities or films. Specifically, the surfaces are “clean” relative to the surfaces of gold nanoparticles made using chemical reduction processes that require organic reductants and/or surfactants to grow gold nanoparticles from gold ions in solution.The invention includes novel electrochemical manufacturing apparatuses and techniques for making the gold-based nanocrystals. The invention further includes pharmaceutical compositions thereof and the use of the gold nanocrystals or suspensions or colloids thereof for the treatment or prevention of diseases or conditions for which gold therapy is already known and more generally for conditions resulting from pathological cellular activation, such as inflammatory (including chronic inflammatory) conditions, autoimmune conditions, hypersensitivity reactions and/or cancerous diseases or conditions. In one embodiment, the condition is mediated by MT (macrophage migration inhibiting factor).

Inventors:
Mark Mortenson
D. Kyle earrings
David Blythe
Adam Dorfman
Reed willcox
Anthony rocket
Micail Mars Rear Cobb
Application Number:
JP2018147599A
Publication Date:
June 03, 2020
Filing Date:
August 06, 2018
Export Citation:
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Assignee:
Clean Nanomedicine, Incorporated
International Classes:
A61K33/242; B22F9/00; A61K9/10; A61K47/02; A61P1/04; A61P19/02; A61P25/04; A61P29/00; A61P29/02; A61P37/06; B22F1/0545; B82Y5/00; B82Y40/00; C25C1/20; C25C5/02
Domestic Patent References:
JP2012532992A
Foreign References:
WO2009009143A1
Attorney, Agent or Firm:
Atsushi Aoki
Shinji Mitsuhashi
Naori Kota
Satoshi Deno
Masatoshi Takahashi
Tetsuji Koga