Title:
新規なヒドロキサム酸誘導体
Document Type and Number:
Japanese Patent JP5763621
Kind Code:
B2
Abstract:
Provided is a novel compound which is useful as a pharmaceutical composition by inhibiting an LpxC activity, thereby exhibiting potent antimicrobial activity against gram-negative bacteria including Pseudomonas aeruginosa and its drug resistant bacteria. Provided is a hydroxamic acid derivative represented by the following general formula [1] or a pharmaceutically acceptable salt thereof:
Inventors:
Takashima Ichi
Risa Tsuruta
Tetsuya Yabuuchi
Yusuke Oka
Urabe Hiroki
Youichiro Suga
Masato Takahashi
Uneshi history
Hironori Kotsubo
Shoji Sosei
Kawaguchi Yasuko
Risa Tsuruta
Tetsuya Yabuuchi
Yusuke Oka
Urabe Hiroki
Youichiro Suga
Masato Takahashi
Uneshi history
Hironori Kotsubo
Shoji Sosei
Kawaguchi Yasuko
Application Number:
JP2012511687A
Publication Date:
August 12, 2015
Filing Date:
April 20, 2011
Export Citation:
Assignee:
Taisho Pharmaceutical Co., Ltd.
Toyama Chemical Co., Ltd.
Toyama Chemical Co., Ltd.
International Classes:
C07C259/06; A61K31/166; A61K31/337; A61K31/341; A61K31/343; A61K31/351; A61K31/357; A61K31/36; A61K31/381; A61K31/397; A61K31/40; A61K31/4015; A61K31/402; A61K31/403; A61K31/4035; A61K31/404; A61K31/4045; A61K31/407; A61K31/415; A61K31/416; A61K31/4164; A61K31/4184; A61K31/42; A61K31/421; A61K31/422; A61K31/4245; A61K31/426; A61K31/428; A61K31/433; A61K31/437; A61K31/438; A61K31/44; A61K31/4402; A61K31/4406; A61K31/4409; A61K31/4418; A61K31/445; A61K31/4453; A61K31/47; A61K31/496; A61K31/5375; A61K31/5377; A61K31/538; A61K31/5386; A61K31/54; A61K31/553; A61P31/04; A61P43/00; C07C317/44; C07C323/62; C07D205/04; C07D205/12; C07D207/10; C07D207/12; C07D207/27; C07D207/327; C07D209/08; C07D209/12; C07D209/14; C07D209/44; C07D209/52; C07D211/14; C07D211/18; C07D211/38; C07D211/46; C07D211/56; C07D211/70; C07D213/38; C07D213/40; C07D213/54; C07D213/61; C07D213/64; C07D213/65; C07D213/70; C07D213/74; C07D213/81; C07D215/14; C07D217/04; C07D217/12; C07D231/12; C07D231/56; C07D233/61; C07D235/04; C07D257/04; C07D261/08; C07D263/14; C07D263/32; C07D263/56; C07D265/30; C07D265/38; C07D267/10; C07D271/12; C07D277/20; C07D277/30; C07D277/62; C07D277/66; C07D285/12; C07D295/08; C07D295/12; C07D295/14; C07D295/16; C07D305/06; C07D305/08; C07D307/14; C07D307/18; C07D307/52; C07D307/54; C07D307/78; C07D307/82; C07D307/87; C07D309/04; C07D309/14; C07D317/30; C07D317/60; C07D319/18; C07D319/20; C07D333/24; C07D405/06; C07D413/06; C07D471/04; C07D471/10; C07D487/08; C07D491/20; C07D498/08
Domestic Patent References:
| JP2007531793A | 2007-11-08 | |||
| JP2007531793A | 2007-11-08 |
Foreign References:
| US20070066646A1 | 2007-03-22 | |||
| WO2000059874A1 | 2000-10-12 |
Attorney, Agent or Firm:
Shinjiro Ono
Yasushi Kobayashi
Hiroyuki Tomita
Osamu Hoshino
Akiko Yamaguchi
Yasushi Kobayashi
Hiroyuki Tomita
Osamu Hoshino
Akiko Yamaguchi