Title:
パ−キンソン病治療用の新規高透過薬物及びその組成物
Document Type and Number:
Japanese Patent JP6987104
Kind Code:
B2
Abstract:
To provide novel high penetration compositions (HPCs) or high penetration prodrugs (HPPs) for treatment of Parkinson's disease.SOLUTION: The HPCs/HPPs are capable of being converted to parent active drugs or drug metabolites after crossing the biological barrier and thus can render treatments for conditions that can be treated by the parent drugs or metabolites. Additionally, the HPPs are capable of reaching areas that parent drugs cannot access or rendering a sufficient concentration at the target areas, and therefore render novel treatments. The HPCs/HPPs can be administered to a subject through various administration routes, e.g., locally delivered to an action site of a condition with a high concentration or systematically administered to a biological subject so as to enter the general circulation with a faster rate.SELECTED DRAWING: None
More Like This:
| JPH0381257 | TREATMENT OF GLAUCOMA |
| JP2022137120 | ANTIVIRAL COMPOUNDS |
| JP4970958 | Hydroaminomethylation of olefins |
Inventors:
You Chongshi
Shurina
Shurina
Application Number:
JP2019178707A
Publication Date:
December 22, 2021
Filing Date:
September 30, 2019
Export Citation:
Assignee:
TechFields Pharma Company Limited
You Chongshi
You Chongshi
International Classes:
C07C237/08; C07C271/16; C07D207/16; C07D211/62; C07D321/12; C07D455/02
Domestic Patent References:
| JP3236317A | ||||
| JP55007242A | ||||
| JP52046033A | ||||
| JP2010138199A | ||||
| JP59070611A | ||||
| JP2012511027A |
Foreign References:
| GB1308259A | ||||
| US4727079 | ||||
| CN1470506A |
Other References:
RN:780714-22-9,DATABASE REGISTRY [ONLINE] Retrieved from STN,2004年11月14日,検索日:2020年9月4日
RN:773015-12-6,DATABASE REGISTRY [ONLINE] Retrieved from STN,2004年10月31日,検索日:2020年9月4日
Yasuda, Masahiro; Nishi, Hiroyuki; Kakimoto, Toshio et al,"Physicochemical properties and stability of docarpamine",Iyakuhin Kenkyu,1992年,Vol.23(3),p.231-240
Mizoguchi, Haruko; Orlowski, Marian; Wilk, Sherwin; Green, Jack Peter,”γ-Glutamyl DOPA and γ-glutamyl dopamine: effect on plasma glucose levels",European Journal of Pharmacology,1979年,Vol.57(2-3),p.239-245
RN:773015-12-6,DATABASE REGISTRY [ONLINE] Retrieved from STN,2004年10月31日,検索日:2020年9月4日
Yasuda, Masahiro; Nishi, Hiroyuki; Kakimoto, Toshio et al,"Physicochemical properties and stability of docarpamine",Iyakuhin Kenkyu,1992年,Vol.23(3),p.231-240
Mizoguchi, Haruko; Orlowski, Marian; Wilk, Sherwin; Green, Jack Peter,”γ-Glutamyl DOPA and γ-glutamyl dopamine: effect on plasma glucose levels",European Journal of Pharmacology,1979年,Vol.57(2-3),p.239-245
Attorney, Agent or Firm:
Shinichiro Tanaka
Hiroyuki Suda
Kazuo Yamazaki
Satsuki Ichikawa
Hironobu Hattori
Shimura
Hiroyuki Suda
Kazuo Yamazaki
Satsuki Ichikawa
Hironobu Hattori
Shimura