Title:
NEW LIGNAN COMPOUND
Document Type and Number:
Japanese Patent JPH01290669
Kind Code:
A
Abstract:
NEW MATERIAL: Lignan compounds represented by formulas I and II.
EXAMPLE: 6S,7SDimethyl-7hydroxy-8hydroxyminimo-2,3-methylenedioxy1,10,11,12- tetramethoxy[S]-dibenzo[a,c] cyclooctadiene.
USE: A remedy against acute or chronic liver diseases such as fatty liver, alcoholic hepatitis, poison liver failure, congestive liver, bile stasis liver failure or liver cirrhosis.
PREPARATION: 6S,7SDimethyl-7-hydroxy8-oxo-2,3methylenedioxy-1,10,11,12 tetramethoxy[S]-dibenzo[a,c] cyclooctadiene is reacted with hydroxyamine hydrochloride in anhydrous pyridine to obtain a compound of formula I, and this is reacted with sulfuric acid or formic acid to obtain a compound of formula II.
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Inventors:
RI REN NIYAN
SHIE HON
RIYUU GAN TAO
UEI HOWAI RIN
AIHARA HIROKAZU
KOTOMO SUSUMU
HIGUCHI SHOHEI
SHIE HON
RIYUU GAN TAO
UEI HOWAI RIN
AIHARA HIROKAZU
KOTOMO SUSUMU
HIGUCHI SHOHEI
Application Number:
JP11232588A
Publication Date:
November 22, 1989
Filing Date:
May 09, 1988
Export Citation:
Assignee:
CHIYUNGUO IISHIYUE KUUUSHIYUEY
TAISHO PHARMACEUTICAL CO LTD
TAISHO PHARMACEUTICAL CO LTD
International Classes:
A61K31/357; A61K31/36; C07D317/70; A61P1/16; (IPC1-7): A61K31/36; C07D317/70
Attorney, Agent or Firm:
Kitagawa Fuzo
Previous Patent: JP1290668
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