NEW MATERIAL:A compound of the formula (R1 is OH; R2 is H, or R1 and R3 may form an epoxy group). The compound of the formula wherein R1 is OH and R2 is H has the following physicochemical properties. Molecular weight: 404; molecular formula: C24H20O6; mass spectrum (EI-MS):m/z 404(M+); solubility: soluble in chloroform, dichloromethane and ethyl acetate; slightly soluble in methanol, ethanol, acetone and n-hexane and insoluble in water; coloring reaction: positive to vanillin-sulfuric acid positive to ferric chloride reaction; acidic; quality and color: yellow crystal, etc.
USE: An anti-tumor drug.
PREPARATION: A strain belonging to the genus Streptomyces such as Streptomyces.species HP 530 strain (FERM BP-2786) is cultured preferably at 30°C for 3-6 days by a deep stirring culture method.
Abe, Naoki
Nakakita, Yasuichi
Uchida, Hideaki
Takeo, Shun
Watanabe, Nobuhiro
