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Title:
NEW MATERIAL AND PREPARATION THEREOF
Document Type and Number:
Japanese Patent JP04117379
Kind Code:
A
Abstract:

NEW MATERIAL:A compound of the formula (R1 is OH; R2 is H, or R1 and R3 may form an epoxy group). The compound of the formula wherein R1 is OH and R2 is H has the following physicochemical properties. Molecular weight: 404; molecular formula: C24H20O6; mass spectrum (EI-MS):m/z 404(M+); solubility: soluble in chloroform, dichloromethane and ethyl acetate; slightly soluble in methanol, ethanol, acetone and n-hexane and insoluble in water; coloring reaction: positive to vanillin-sulfuric acid positive to ferric chloride reaction; acidic; quality and color: yellow crystal, etc.

USE: An anti-tumor drug.

PREPARATION: A strain belonging to the genus Streptomyces such as Streptomyces.species HP 530 strain (FERM BP-2786) is cultured preferably at 30°C for 3-6 days by a deep stirring culture method.


Inventors:
Enoki, Nobuyasu
Abe, Naoki
Nakakita, Yasuichi
Uchida, Hideaki
Takeo, Shun
Watanabe, Nobuhiro
Application Number:
JP1990000233315
Publication Date:
April 17, 1992
Filing Date:
September 05, 1990
Export Citation:
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Assignee:
SAPPORO BREWERIES LTD
International Classes:
C12P17/06; A61K31/35; A61K31/352; A61P35/00; C07D311/78; C07D407/04; C12R1/465; C12P17/02; A61K31/35; A61K31/352; A61P35/00; C07D311/00; C07D407/00; (IPC1-7): A61K31/35; C07D311/78; C07D407/04; C12P17/06