To obtain a new phenylalanine derivative represented by a specified formula, having an antagonistic effect on a disease damage to a fruit tree and a fungus of a human and an animal and useful as a bacteriocide for a horticultural fruit tree and an antifungal agent for a medical treatment.
This new phenylalanine derivative is represented by formula I [R1 is H or a 1-8C alkyl; R2 is H, a 1-8C alkyl, a 1-6C alkoxycarbonyl, a 1-6C alkylcarbonyl, etc.; R3' is a group of the formula OR4 (R4 is H, a 3-18C alkyl, a 3-8C haloalkyl, etc.), etc.] and exemplified by N-(p-toluenesulfonyl)-4- fluorophenylaranine, etc. Moreover, the compound is obtained, for example, by the reaction, etc., using a compound represented by formula II [X is a halogen or nitro; (m) is 1-2] as a starting material under the existence of alcohols at the temperature between -20°C and about the boiling temperature of the solvent for 0.5-24 hours.
UMIMOTO KOUJI
NISHIGUCHI TSUTOMU
BABA KOJI
TABUCHI TATSUO
YOSHIDA MASANORI
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