To obtain new polynucleotide and polypeptide sequences participating in a G protein conjugated-type receptor.
This polypeptide sequence includes one or more (a) polypeptide containing a presumed amino acid sequence translated from a specific polynucleotide sequence derived from human beings or its mutant, fragment, homologue, analogue and derivative or (b) specific polypeptide derived from human beings or its mutant, fragment, homologue, analogue and derivative. The antibody against the above polypeptide, the compound regulating the polypeptide, the preparation composition including the above antibody or compound and one or more pharmaceutically permissible carriers, diluents, adjuvants or vehicles and the above antibody or compound are utilized as medicinal compositions.