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Title:
NEW POLYPEPTIDE
Document Type and Number:
Japanese Patent JP2001352986
Kind Code:
A
Abstract:

To provide a polypeptide useful for screening for and/or developing an agent for treating, preventing, and/or diagnosing a disease related to the activation of NF-κB, a DNA encoding the polypeptide, an antisense DNA/RNA of the DNA the gene therapy using the DNA, an antibody recognizing the polypeptide, a modified polypeptide derived from the preceding polypeptide and having an enhanced activity, a dominant negative variant of the polypeptide, and methods for utilizing these.

A polypeptide activating NF-κB is identified to produce a DNA encoding the polypeptide and an antibody recognizing the polypeptide. These can be utilized fro screening for a medicine for and diagnosing a disease related to the activation of NF-κB.


Inventors:
Obata, Choei
Nishi, Tatsuya
Ota, Norio
Nakamura, Yusuke
Sugano, Sumio
Application Number:
JP2000000175475
Publication Date:
December 25, 2001
Filing Date:
June 12, 2000
Export Citation:
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Assignee:
KYOWA HAKKO KOGYO CO LTD
International Classes:
A01H5/00; A01K67/027; A01K67/033; A61K38/00; A61K39/395; A61K48/00; A61P3/10; A61P9/04; A61P9/10; A61P11/00; A61P11/02; A61P11/04; A61P11/06; A61P13/12; A61P17/06; A61P19/02; A61P19/06; A61P19/10; A61P31/00; A61P31/12; A61P31/18; A61P35/00; A61P35/02; A61P37/04; A61P37/08; A61P43/00; C07K14/47; C07K16/18; C12N1/21; C12N5/10; C12N15/09; C12P21/02; C12P21/08; C12Q1/68; G01N33/15; G01N33/50; G01N33/53; G01N33/566; C12R1/19; C12R1/91; (IPC1-7): C12N15/09; A01H5/00; A01K67/027; A01K67/033; A61K38/00; A61K39/395; A61K48/00; A61P3/10; A61P9/04; A61P9/10; A61P11/00; A61P11/02; A61P11/04; A61P11/06; A61P13/12; A61P17/06; A61P19/02; A61P19/06; A61P19/10; A61P31/00; A61P31/12; A61P31/18; A61P35/00; A61P35/02; A61P37/04; A61P37/08; A61P43/00; C07K14/47; C07K16/18; C12N1/21; C12N5/10; C12P21/02; C12Q1/68; G01N33/15; G01N33/50; G01N33/53; G01N33/566



 
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