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Title:
新規のポルフィリン誘導体、特にクロリン及び/又はバクテリオクロリン、並びに光線力学療法におけるその適用
Document Type and Number:
Japanese Patent JP5226317
Kind Code:
B2
Abstract:
The invention relates to derivatives of porphyrin, particularly chlorins and/or bacteriochlorins, which can be used in photodynamic therapy. According to the formulas of the invention, X1, X2, X3, X4, X5, X6, X7, X8, which may be identical or different, each represent halogen atoms or hydrogen atoms. R1, R2, R3, R4, which may be identical or different, are each selected from the following groups: -OH, amino acids, -OR and -NHR and/or a chlorine atom, wherein R is an alkyl group having between 1 and 12 carbon atoms. The invention also relates to an anticancer and/or antiviral and/or antimicrobial medicament for human or animal use, which contains one or more compounds as the main active ingredient.

Inventors:
Migens, Pereira Maria
Arnout Moreira, Luis Gilhelme
Formosa Shinho Simonys, Sebastian O Jose
Monteiro, Carlos
Application Number:
JP2007540608A
Publication Date:
July 03, 2013
Filing Date:
November 10, 2005
Export Citation:
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Assignee:
Universidade de Coimbra
International Classes:
C07D487/22; A01N43/713; A01P1/00; A61K31/409; A61P31/04; A61P31/12; A61P35/00
Domestic Patent References:
JP1275583A
Foreign References:
WO2003020309A1
WO2003064427A1
Other References:
Banfi,S.et al,Bioorganic & Medicinal Chemistry,2003年,Vol.11,pp 3595-3605
Attorney, Agent or Firm:
Atsushi Aoki
Takashi Ishida
Fukumoto product
Tetsuji Koga
Kazuhiro Nakamura